DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9b2 and Cyp4f39

DIOPT Version :9

Sequence 1:	NP_523646.1	Gene:	Cyp9b2 / 35635	FlyBaseID:	FBgn0015039	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	XP_006241152.1	Gene:	Cyp4f39 / 299566	RGDID:	1308796	Length:	550	Species:	Rattus norvegicus

Alignment Length:	565	Identity:	122/565 - (21%)
Similarity:	212/565 - (37%)	Gaps:	126/565 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LVVIGYLIYKWSTATFKTFEERKLYFEK----PYP-----FVGNMAAAALQKSSFQRQLTEFYER 65
            |:.:.:|:::.....||.|.:.::...:    |.|     .:|:|:.....:...|.:....  .
  Rat    28 LLFLLFLLFRLLLQAFKLFSDFRITCRRLSCFPEPPGRHWLLGHMSMYLPNEKGLQNEKKVL--D 90

  Fly    66 TRQHKLVGFFNMRTPMITLNDPELIKKVCVKDFDHFPNHQPFITSNDRLFNDMLSVMRDQRWKHM 130
            |..|.::.:.....|::.|..|:.||.|........|..:.|.:.......|.|.:.:..:|...
  Rat    91 TMHHIILAWVGPFLPLLVLVHPDYIKPVLGASAAIAPKDEFFYSFLKPWLGDGLLISKGNKWSRH 155

  Fly   131 RNTLTPVFTAAKMRNMFTLMNES----FAECLQHLDSSSKTLPGRKGFEVDMKVMCNKLSNDIIA 191
            |..|||.|....::....:.|:|    .|:..:||...|.|       ..||....:.::.|.:.
  Rat   156 RRLLTPAFHFDILKPYMKIFNQSVNIMHAKWRRHLAEGSVT-------SFDMFEHVSLMTLDSLQ 213

  Fly   192 TTAFGLKVNSYDNPKNEFYEIGQSLVFSRGLQFFKFMLSTLVPKLFSLLKLTIFDSAK----VDY 252
            ...|     ||.:...|                   .||..:..:..|..|.:....:    :|:
  Rat   214 KCVF-----SYSSDCQE-------------------KLSDYISSIIELSALVVRRQYRLHHYLDF 254

  Fly   253 FARLVVEAMQYREK----HNITRP--------------------------DMIQLLMEAKNESED 287
            ...|..:..::|:.    ||.|..                          |.|.:|:.||:|...
  Rat   255 IYYLTADGRRFRQACDTVHNFTTEVIQQRRRALRELGAEAWLKAKQGKTLDFIDVLLLAKDEEGK 319

  Fly   288 KWTDDEIVAQCFIFFFAAFENNSNLICTTTYELLYNPDVQERLYEEIVETKKALNGAPLTYDAVQ 352
            :.:|::|.|:...|.|...:..|:.:....:.|...|:.|::..|||.|..|......|.:|.:.
  Rat   320 ELSDEDIRAEADTFMFEGHDTTSSGLSWALFNLAKYPEYQDKCREEIQEVMKGRELEELDWDDLT 384

  Fly   353 KMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFDFKVGDRINIP--------ISGLH 409
            ::.:..|.|.||||::.......|.|::|..|.|            .|| ||        |.|.|
  Rat   385 QLPFTTMCIKESLRQFPPVTLISRRCTEDIKLPD------------GRI-IPKGIICLVSIYGTH 436

  Fly   410 LDDRYFPEPRKFDPDRFSEERKGDMVPYTYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHY---- 470
            .:...:|:.:.::|.||..:......|..::||..|||||||..:|:.:::.::...||.:
  Rat   437 YNPLVWPDSKVYNPYRFDPDIPQQRSPLAFVPFSAGPRNCIGQSFAMAEMRVVVALTLLRFRLSV 501

  Fly   471 ----KIEASP----RTIKDLWGSASGFNFTP---RSGFWMHLVPR 504
                |:...|    ||...||     .|..|   |:|     |||
  Rat   502 DRTRKVRRKPELILRTENGLW-----LNVEPLPSRAG-----VPR 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	p450	37..478	CDD:299894	106/507 (21%)
Cyp4f39	XP_006241152.1	CYP4F	82..523	CDD:410772	106/491 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900