Protein Alignment Cyp9b2 and CYP4V2

DIOPT Version :9

• Sequence 1: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_997235.3
• Gene: CYP4V2 / 285440
• HGNCID: 23198
• Length: 525
• Species: Homo sapiens
• Alignment Length: 516
• Identity: 119/516 - (23%)
• Similarity: 213/516 - (41%)
• Gaps: 98/516 - (18%)

  Fly    37 KPYPFVGNMAAAALQKSSFQRQLTEFYERTRQHKLVGFFNMRTPMITLNDPELIKKVCVKDFDHF 101
            :.||.||:..........|.:|:.|:.|..|...|:..:....||:.|.:.|
Human    55 RAYPLVGHALLMKPDGREFFQQIIEYTEEYRHMPLLKLWVGPVPMVALYNAE------------- 106

  Fly   102 PNHQPFITSNDRLFNDMLSVMR--------------DQRWKHMRNTLTPVFTAAKMRNMFTLMNE 152
             |.:..:||:.::  |..|:.:              ..:|:..|..|||.|....:.:...:|||
Human   107 -NVEVILTSSKQI--DKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNE 168

  Fly   153 SFAECLQHLDSSSKTLPGRKGFEVDMKV-MCNKLSNDIIATTAFGLKVNSYDNPKNEF----YEI 212
            .....::.|:...    .::.|.....: :|   :.|||..||.|..:.:..|..:|:    |.:
Human   169 QANILVKKLEKHI----NQEAFNCFFYITLC---ALDIICETAMGKNIGAQSNDDSEYVRAVYRM 226

  Fly   213 GQS----------------LVFSRGLQFFKFMLSTLVPKLFSLLKLTIFDSAKVDYFARLVVEAM 261
            .:.                |:|..|.:..|           ||..|..|.::       ::.|..
Human   227 SEMIFRRIKMPWLWLDLWYLMFKEGWEHKK-----------SLQILHTFTNS-------VIAERA 273

  Fly   262 QYREKHNITRPD-------------MIQLLMEAKNESEDKWTDDEIVAQCFIFFFAAFENNSNLI 313
            .....:...|.|             .:.||:...::..::.:.::|..:...|.|...:..:..|
Human   274 NEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAI 338

  Fly   314 CTTTYELLYNPDVQERLYEEIVETKKALNGAPLTYDAVQKMTYMDMVISESLRKWTLAAATDRLC 378
            ..:.|.|..||:||:::..|: :.....:..|.|.:.::|:.|::.||.|:||.:.......|..
Human   339 NWSLYLLGSNPEVQKKVDHEL-DDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSV 402

  Fly   379 SKDYTLTDDDGTKLFDFKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPYTYLPFG 443
            |:|..:.   |.::  .|..:.:.||.: ||.|.||||.|.:|.|:||..|......||.|:||.
Human   403 SEDCEVA---GYRV--LKGTEAVIIPYA-LHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFS 461

  Fly   444 VGPRNCIGNRYALMQVKGMLFNLLLHYKIEASPRTIKDLWGSASGFNFTPRSGFWMHLVPR 504
            .|||||||.::|:|:.|.:|..:|.|:.||::.:  ::..|........|.:|.|:.|..|
Human   462 AGPRNCIGQKFAVMEEKTILSCILRHFWIESNQK--REELGLEGQLILRPSNGIWIKLKRR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	p450	37..478	CDD:299894	113/488 (23%)
CYP4V2	NP_997235.3	p450	55..517	CDD:278495	117/511 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900