Protein Alignment Cyp9b2 and CYP4A22

DIOPT Version :9

• Sequence 1: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001010969.2
• Gene: CYP4A22 / 284541
• HGNCID: 20575
• Length: 519
• Species: Homo sapiens
• Alignment Length: 521
• Identity: 121/521 - (23%)
• Similarity: 195/521 - (37%)
• Gaps: 99/521 - (19%)

  Fly     2 ALIEICLALVVIG--YLIYKWSTATFKTFEERKLYFEKPYPFVGNMAAAALQKSSFQRQLTEFYE 64
            :|:.:.|.|:...  ||..:|.....:.|         |.| ..:.....:|:....::|....|
Human    23 SLLILLLLLIKAAQLYLHRQWLLKALQQF---------PCP-PSHWLFGHIQEFQHDQELQRIQE 77

  Fly    65 RTRQHKLVGFFNMRTP--------MITLNDPELIKKVCVKDFDHFPNHQPFITSNDRLFNDMLSV 121
            |.:.      |....|        .:.|.||:.:|.:..:..........|:.  .|:...:| :
Human    78 RVKT------FPSACPYWIWGGKVRVQLYDPDYMKVILGRSDPKSHGSYKFLA--PRIGYGLL-L 133

  Fly   122 MRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGFEVDMKVMCNKLS 186
            :..|.|...|..|||.|....::....||.:|....   ||...:.|......||...|  :.::
Human   134 LNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVM---LDKWEELLGQDSPLEVFQHV--SLMT 193

  Fly   187 NDIIATTAFGLKVNSYDNPKNEFYEIGQSLVFSRGLQFFKFMLSTLVPKLFSLLKL------TIF 245
            .|.|..:||     |:..          |:...|..|.:...:|.|...:|..::.      ||:
Human   194 LDTIMKSAF-----SHQG----------SIQVDRNSQSYIQAISDLNSLVFCCMRNAFHENDTIY 243

  Fly   246 DSAKVDYFARLVVEAMQYREKH-------------------NITRP---DMIQLLMEAKNESEDK 288
            .....   .|....|.|...:|                   .|.|.   |.:.:|:.||.|:...
Human   244 SLTSA---GRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEKIKRKRHLDFLDILLLAKMENGSI 305

  Fly   289 WTDDEIVAQCFIFFFAAFENNSNLICTTTYELLYNPDVQERLYEEIVETKKAL--NGAPLTYDAV 351
            .:|.::.|:...|.|...:..::.|....|.|..:|..|||..|||    ..|  :||.:|::.:
Human   306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEI----HGLLGDGASITWNHL 366

  Fly   352 QKMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFDFKVGDRINIPISGLHLDDRYFP 416
            .:|.|..|.|.|:||.:.......|..|...|.  .||..|   ..|..:.:.|.|||.:.:.:|
Human   367 DQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF--PDGRSL---PKGIMVLLSIYGLHHNPKVWP 426

  Fly   417 EPRKFDPDRF---SEERKGDMVPYTYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASPRT 478
            ....|||.||   |.:..     :.:|||..|.|||||.::|:.|:|......||.:::...|..
Human   427 NLEVFDPSRFAPGSAQHS-----HAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTR 486

  Fly   479 I 479
            |
Human   487 I 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	p450	37..478	CDD:299894	113/481 (23%)
CYP4A22	NP_001010969.2	p450	52..505	CDD:278495	114/483 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900