Protein Alignment Cyp9b2 and CYP4Z1

DIOPT Version :9

• Sequence 1: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_835235.1
• Gene: CYP4Z1 / 199974
• HGNCID: 20583
• Length: 505
• Species: Homo sapiens
• Alignment Length: 533
• Identity: 132/533 - (24%)
• Similarity: 217/533 - (40%)
• Gaps: 133/533 - (24%)

  Fly     1 MALIEICLALVVIGYL-IY---KWSTATFKTFEERKLYFEKPYP----FVGNMAAAALQKSSFQR 57
            :.||.:|::|::...: :|   :|.......|         |.|    |.|:
Human    15 LLLILLCMSLLLFQVIRLYQRRRWMIRALHLF---------PAPPAHWFYGH------------- 57

  Fly    58 QLTEFY---ERTRQHKL-----------VGFFNMRTPMITLNDPELIKKVCVKDFDHFPNHQPFI 108
              .|||   |....|||           ||.|.|   ..:::||: ..|:.:|..|      |..
Human    58 --KEFYPVKEFEVYHKLMEKYPCAVPLWVGPFTM---FFSVHDPD-YAKILLKRQD------PKS 110

  Fly   109 TSNDRLFNDM----LSVMRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESF--------------- 154
            ..:.::....    |..:...:||..|..:.|.|..:.::...|:|:||.
Human   111 AVSHKILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNS 175

  Fly   155 -AECLQH-----LDSSSKTLPGRKG-FEVD------MKVMCN--KLSNDIIATTAFGLKVNSYDN 204
             .|..||     |||..|.....:| .::|      :|.:.|  |:||.         ::|::.:
Human   176 RLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQ---------RMNNFLH 231

  Fly   205 PKNEFYEIGQSLVF---SRGLQFFKF--MLSTLVPKLFSLLKLTIFDSAKVDYFARLVVEAMQYR 264
            ..:        |||   |:|..|.||  .|.....|:....|.::.|..|.|        ..|.|
Human   232 HND--------LVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKDKLKQD--------TTQKR 280

  Fly   265 EKHNITRPDMIQLLMEAKNESEDKWTDDEIVAQCFIFFFAAFENNSNLICTTTYELLYNPDVQER 329
                  |.|.:.:|:.||:|:...:::.::.|:...|.||..:..|:.|....|.|...|:.|:|
Human   281 ------RWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQR 339

  Fly   330 LYEEIVETKKALNGAPLTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFD 394
            ..:||.|...  :|:.:|::.:.:|.|..|.|.|.||.:.......||..|  .:|..||..|
Human   340 CRDEIRELLG--DGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDK--PITFPDGRSL-- 398

  Fly   395 FKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPYTYLPFGVGPRNCIGNRYALMQV 459
             ..|..:.|.|..||.:..::.:|:.|:|.|||.|....:.||.::||..|.|||||..:|:::.
Human   399 -PAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIEC 462

  Fly   460 KGMLFNLLLHYKI 472
            |..:...||.:|:
Human   463 KVAVALTLLRFKL 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	p450	37..478	CDD:299894	125/493 (25%)
CYP4Z1	NP_835235.1	p450	47..500	CDD:278495	125/492 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900