Protein Alignment Cyp9b2 and cyp-13A4

DIOPT Version :10

• Sequence 1: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_496111.1
• Gene: cyp-13A4 / 188355
• WormBaseID: WBGene00011671
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 566
• Identity: 150/566 - (26%)
• Similarity: 253/566 - (44%)
• Gaps: 111/566 - (19%)

  Fly     1 MALIEICLALVVIGYLIYK---WSTATFKTFEERK-LYFEKPYPFVGNMAAAALQKSSFQRQ-LT 60
            |:|..:....:.||:|.|.   ||      |..|| :...:.:||.|    ..|:...::.. |.
 Worm     1 MSLSLLIAGALFIGFLTYYIWIWS------FWIRKGVKGPRGFPFFG----VILKFHDYENPGLL 55

  Fly    61 EFYERTRQH-KLVGFFNMRTPMITLNDPELIKKVCVKDFDHF-----------PNHQPFITSNDR 113
            :..|.|::: .:.|........:.:::||.:.:|.||.||:|           ||      .|.|
 Worm    56 KLGEWTKKYGSIYGITEGVEKTLVVSNPEFVHEVFVKQFDNFYGRKTNPIQGDPN------KNKR 114

  Fly   114 LFNDMLSVMRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGFEVDM 178
            ..   |.:.:..|||.:|...:|.|:...:|.:.:.:.|:..|.::|||.:|     .||..||:
 Worm   115 AH---LVLAQGHRWKRLRTLASPTFSNKSLRKIMSTVEETVVELMRHLDEAS-----AKGKAVDL 171

  Fly   179 KVMCNKLSNDIIATTAFGLKVN-SYDNPK----NEFYEIGQSLVF------------SRGLQFFK 226
            .....:.:.|||...|.|...: .:.||.    .|.::.|..:.|            .|.| |.|
 Worm   172 LDYYQEFTLDIIGRIAMGQTESLMFRNPMLPKVKEIFKKGGKMPFLIAGVFPIAGTLMRQL-FMK 235

  Fly   227 F--------MLSTLVPKLFSLL-------KLTIFDSAKVDYFARLVVEAMQYREKHNITRPDMIQ 276
            |        :::|:...|...|       |..|..|.:...|..|.::|     :.|:...:...
 Worm   236 FPKFSPAFGIMNTMEKALNKRLEQRAADKKAGIEPSGEPQDFIDLFLDA-----RANVDFIEEES 295

  Fly   277 LLMEAKNE--SEDK-WTDDEIVAQCFIFFFAAFENNSNLICTTTYELLYNPDVQERLYEEIVETK 338
            .|..||:|  ..|| .|.|||:.|.|:|..|.::..:..:..::|.|..:|::|::|.||:   .
 Worm   296 TLGFAKSEVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEV---D 357

  Fly   339 KALNGAPLTYDAVQKMTYMDMVISESLRKWTLAAAT-DRLCSKDYTLTDDDGTKLFDFKVGDRIN 402
            :......:|:|.:.|:.||:.|:.|:||.:.||:.. :|.|.|.        |.:...::.:..|
 Worm   358 RECPDPEVTFDQISKLKYMECVVKEALRMYPLASLVHNRKCMKK--------TNVLGVEIDEGTN 414

  Fly   403 IPIS--GLHLDDRYF-PEPRKFDPDRFSEERKGDMVPYT---YLPFGVGPRNCIGNRYALMQVKG 461
            :.:.  .||.|.:.: .:..:|.|:|:   ..||.:.|.   |||||:|||.|||.|.|:|:.|.
 Worm   415 VQVDTWTLHYDPKVWGDDASEFKPERW---ETGDELFYAKGGYLPFGMGPRICIGMRLAMMEEKL 476

  Fly   462 MLFNLLLHYKIEASPRT---IKDLWGSASGFNFTPRSGFWMHLVPR 504
            :|.::|..|..:.|..|   :| |.|||:   ..||: ..:.|.||
 Worm   477 LLTHILKKYTFDTSTETEIPLK-LVGSAT---IAPRN-VMLKLTPR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	CYP6-like	67..498	CDD:410679	129/487 (26%)
cyp-13A4	NP_496111.1	CYP3A-like	63..511	CDD:410678	129/486 (27%)