DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9b2 and cyp-31A2

DIOPT Version :9

Sequence 1:	NP_523646.1	Gene:	Cyp9b2 / 35635	FlyBaseID:	FBgn0015039	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_502152.3	Gene:	cyp-31A2 / 178065	WormBaseID:	WBGene00010354	Length:	495	Species:	Caenorhabditis elegans

Alignment Length:	507	Identity:	115/507 - (22%)
Similarity:	206/507 - (40%)	Gaps:	91/507 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ICLAL-VVIGYLIYKWSTATFKTFEERKL--YFEKP--YPFVGNMAAAALQKSSFQRQ---LTEF 62
            :.||: .||.:|:|       |....|::  :..:|  ||.||:..........|..|   :...
Worm     8 VLLAMATVIAWLLY-------KHLRMRQVLKHLNQPRSYPIVGHGLITKPDPEGFMNQVIGMGYL 65

  Fly    63 YERTRQHKL-VGFFNMRTPMITLNDPELIKKVCVKDFDHFPNHQPFITSNDRLFNDMLSVMRDQR 126
            |...|...| :|.|    |.:.|...:|::.: .....|......::.....|...:|:..::|
Worm    66 YPDPRMCLLWIGPF----PCLMLYSADLVEPI-FSSTKHLNKGFAYVLLEPWLGISILTSQKEQ- 124

  Fly   127 WKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHL-----DSSSKTLPGRKGFEVDMKVMCNKLS 186
            |:..|..|||.|....:::...:.||.....:|.|     |.           |||:..:....:
Worm   125 WRPKRKLLTPTFHYDILKDFLPIFNEQSKILVQKLCCLGADE-----------EVDVLSVITLCT 178

  Fly   187 NDIIATTAFGLKVNSYDNPKNEF----YEIGQSLVFSRGLQFFKFMLSTLVPKLFSLLKLTIFDS 247
            .|||..|:.|..:.:.....||:    :.|.: |:..|          |..|.:::.....:.:.
Worm   179 LDIICETSMGKAIGAQLAENNEYVWAVHTINK-LISKR----------TNNPLMWNSFIYNLTED 232

  Fly   248 AKV---------DYFARLVV---EAMQYREKHNITRPDMIQLLMEAKNESEDKWTDDEIVAQCFI 300
            .:.         |:..:::|   ||:|..:.....|...:.||:|.....:...||  :.|:...
Worm   233 GRTHEKCLRILHDFTKKVIVERKEALQENDYKMEGRLAFLDLLLEMVKSGQMDETD--VQAEVDT 295

  Fly   301 FFFAAFENNSNLICTTTYELLYNPDVQERLYEEIVETKKALNGAPLTYDAVQKMTYMDMVISESL 365
            |.|...:..|..:....:.|..:|:||.::..|:.|...  :...:|.:.:.:|.|::..:.|:|
Worm   296 FMFEGHDTTSTGLMWAIHLLGNHPEVQRKVQAELDEVMG--DDEDVTIEHLSRMKYLECALKEAL 358

  Fly   366 RKWTLAAATDRLCSKDYTLTDDDGTKLFDFKVGDRINIP--------ISGLHLDDRYFPEPRKFD 422
            |.:.......|      .|:||        :|...:|||        :..:|.|...:.:|..||
Worm   359 RLFPSVPIITR------ELSDD--------QVIGGVNIPKGVTFLLNLYLVHRDPAQWKDPDVFD 409

  Fly   423 PDRFSEERKGDMVPYTYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEA 474
            ||||..|.......:.::||..|.|||||.|:|||:.|.::.:||.::.|:|
Worm   410 PDRFLPENSIGRKSFAFIPFSAGSRNCIGQRFALMEEKVIMAHLLRNFNIKA 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	p450	37..478	CDD:299894	107/473 (23%)
cyp-31A2	NP_502152.3	p450	36..472	CDD:278495	107/472 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900