Protein Alignment Cyp9b2 and CYP4A11

DIOPT Version :9

• Sequence 1: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_000769.2
• Gene: CYP4A11 / 1579
• HGNCID: 2642
• Length: 519
• Species: Homo sapiens
• Alignment Length: 465
• Identity: 113/465 - (24%)
• Similarity: 185/465 - (39%)
• Gaps: 83/465 - (17%)

  Fly    57 RQLTEFYERTRQHKLVGFFNMRTP--------MITLNDPELIKKVC----VKDFDHFPNHQPFIT 109
            ::|.:..|..|..|.|..|....|        .:.|.||:.:|.:.    .|....:....|:|.
Human    64 QELQQDQELQRIQKWVETFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGSYRFLAPWIG 128

  Fly   110 SNDRLFNDMLSVMRDQRWKHMRNTLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGF 174
            ..       |.::..|.|...|..|||.|....::....||.:|....   ||...:.|......
Human   129 YG-------LLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVM---LDKWEELLGQDSPL 183

  Fly   175 EVDMKVMCNKLSNDIIATTAF----GLKVNSYDNPKNEFYEIG--QSLVFSRGLQFFK-----FM 228
            ||...|  :.::.|.|...||    .::|:.  |.::....|.  .:|||||....|.     :.
Human   184 EVFQHV--SLMTLDTIMKCAFSHQGSIQVDR--NSQSYIQAISDLNNLVFSRVRNAFHQNDTIYS 244

  Fly   229 LSTL--------------VPKLFSLLKLTIFDSAKVDYFARLVVEAMQYREKHNITRPDMIQLLM 279
            |::.              ..::..|.|..:....:::...         |::|    .|.:.:|:
Human   245 LTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEKIK---------RKRH----LDFLDILL 296

  Fly   280 EAKNESEDKWTDDEIVAQCFIFFFAAFENNSNLICTTTYELLYNPDVQERLYEEIVETKKAL--N 342
            .||.|:....:|.::.|:...|.|...:..::.|....|.|..:|..|||..|||    .:|  :
Human   297 LAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEI----HSLLGD 357

  Fly   343 GAPLTYDAVQKMTYMDMVISESLRKWTLAAATDRLCSKDYTLTDDDGTKLFDFKVGDRINIPISG 407
            ||.:|::.:.:|.|..|.|.|:||.:.......|..|...|.  .||..|   ..|..:.:.|.|
Human   358 GASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF--PDGRSL---PKGIMVLLSIYG 417

  Fly   408 LHLDDRYFPEPRKFDPDRF---SEERKGDMVPYTYLPFGVGPRNCIGNRYALMQVKGMLFNLLLH 469
            ||.:.:.:|.|..|||.||   |.:..     :.:|||..|.|||||.::|:.::|......||.
Human   418 LHHNPKVWPNPEVFDPFRFAPGSAQHS-----HAFLPFSGGSRNCIGKQFAMNELKVATALTLLR 477

  Fly   470 YKIEASPRTI 479
            :::...|..|
Human   478 FELLPDPTRI 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	p450	37..478	CDD:299894	112/462 (24%)
CYP4A11	NP_000769.2	p450	52..505	CDD:278495	113/465 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900