Protein Alignment Cyp9b2 and CYP3A7

DIOPT Version :9

• Sequence 1: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_000756.3
• Gene: CYP3A7 / 1551
• HGNCID: 2640
• Length: 503
• Species: Homo sapiens
• Alignment Length: 491
• Identity: 156/491 - (31%)
• Similarity: 268/491 - (54%)
• Gaps: 44/491 - (8%)

  Fly     4 IEICLALVVIGYLIYKWSTATFKTFEERKLYFEKPYPFVGNMAAAALQKSSFQRQLTEFYERTRQ 68
            :|..|.|.|...|:|.:.|.|...|::..:....|.||:||  |.:.:|..:...: |.|::.|
Human     9 VETWLLLAVSLILLYLYGTRTHGLFKKLGIPGPTPLPFLGN--ALSFRKGYWTFDM-ECYKKYR- 69

  Fly    69 HKLVGFFNMRTPMITLNDPELIKKVCVKD-FDHFPNHQPFITSNDRLFNDMLSVMRDQRWKHMRN 132
             |:.|.::.:.||:.:.||::||.|.||: :..|.|.:||  .......:.:|:..|:.||.:|:
Human    70 -KVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRRPF--GPVGFMKNAISIAEDEEWKRIRS 131

  Fly   133 TLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGFEVDMKVMCNKLSNDIIATTAFGL 197
            .|:|.||:.|::.|..::.:.....:::|...::|     |..|.:|.:....|.|:|.:|:||:
Human   132 LLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAET-----GKPVTLKHVFGAYSMDVITSTSFGV 191

  Fly   198 KVNSYDNPKNEFYEIGQSLV-------FSRGLQFFKFMLSTLVPKLFSLLKLTIFDSAKVDYFAR 255
            .::|.:||::.|.|..:.|:       |...::.|.|    |.| :...|.:|:|....:.:..:
Human   192 SIDSLNNPQDPFVENTKKLLRFNPLDPFVLSIKVFPF----LTP-ILEALNITVFPRKVISFLTK 251

  Fly   256 LVVEAMQYR----EKHNITRPDMIQLLMEAKN----ESEDKWTDDEIVAQCFIFFFAAFENNSNL 312
            .|.:..:.|    :||   |.|.:||:::::|    |:....:|.|::||..||.||.:|..|::
Human   252 SVKQIKEGRLKETQKH---RVDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSV 313

  Fly   313 ICTTTYELLYNPDVQERLYEEIVETKKALNGAPLTYDAVQKMTYMDMVISESLRKWTLAAATDRL 377
            :....|||..:||||:::.:||.....  |.||.|||.|.::.|:|||::|:||.:.:|...:|:
Human   314 LSFIIYELATHPDVQQKVQKEIDTVLP--NKAPPTYDTVLQLEYLDMVVNETLRLFPVAMRLERV 376

  Fly   378 CSKDYTLTDDDGTKLFDFKVGDRINIPISGLHLDDRYFPEPRKFDPDRFSEERKGDMVPYTYLPF 442
            |.||..:..     :|..| |..:.||...||.|.:|:.||.||.|:|||::.|.::.||.|.||
Human   377 CKKDVEING-----MFIPK-GVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPF 435

  Fly   443 GVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASPRT 478
            |.|||||||.|:||:.:|..|..:|.::..:....|
Human   436 GSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKET 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	p450	37..478	CDD:299894	146/456 (32%)
CYP3A7	NP_000756.3	p450	39..492	CDD:365848	147/461 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	262	1.000	Domainoid score	I1946
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	277	1.000	Inparanoid score	I2940
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.870