Protein Alignment Cyp9b2 and Cyp46a1

DIOPT Version :10

• Sequence 1: NP_523646.1
• Gene: Cyp9b2 / 35635
• FlyBaseID: FBgn0015039
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Alignment Length: 509
• Identity: 120/509 - (23%)
• Similarity: 203/509 - (39%)
• Gaps: 130/509 - (25%)

  Fly    12 VIGYLIYKW--STATFKTFEERKLYFEKPY-PFVGNMAAAALQKSSFQRQLTEFYERTRQHKLVG 73
            ::|:|.|.|  .....:..::..|.:.|.| |.|               ::..||:.:
Mouse    42 LLGHLPYFWKKDEDCGRVLQDVFLDWAKKYGPVV---------------RVNVFYKTS------- 84

  Fly    74 FFNMRTPMITLNDPELIKKVCV-----KDFDHFPNHQPFITSNDRLFND-MLSVMRDQRWKHMRN 132
                    :.:..||.:||..:     ||...:...|...  .:|||.. ::|.....||...|.
Mouse    85 --------VIVTSPESVKKFLMSTKYNKDSKMYRALQTVF--GERLFGQGLVSECDYGRWYKQRK 139

  Fly   133 TLTPVFTAAKMRNMFTLMNESFAECLQHLDSSSKTLPGRKGFEVDMKVMCNKLSNDIIATTAFGL 197
            .:...|:.:.:.::....||...:.::.|::.:   .|:.  .|.|:.|....:.||:|..|||:
Mouse   140 VMDLAFSRSSLVSLMETFNEKAEQLVEILEAKA---DGQT--PVSMQDMLTCATIDILAKAAFGM 199

  Fly   198 KVNSYDNPKNEFYEIGQSLVFSRGLQFFKFMLSTLVPKLFSLLKLTIFDSAKVDYFARLV----V 258
            :.:..         :|.....|   |..|.||..:              ||..:..|:.:    .
Mouse   200 ETSML---------LGAQKPLS---QAVKVMLEGI--------------SASRNTLAKFMPGKRK 238

  Fly   259 EAMQYREKHNITR---PDMIQLLMEAKNESEDK--------------WTDDEIVAQCFI-FFFAA 305
            :..:.||...:.|   .|.:|...||....||.              ..|||::...|: ||.|.
Mouse   239 QLREIRESIRLLRQVGKDWVQRRREALKRGEDMPADILTQILKAEEGAQDDEVLLDNFVTFFIAG 303

  Fly   306 FENNSNLICTTTYELLYNPDVQERL---YEEIVETKKALNGAPLTYDAVQKMTYMDMVISESLRK 367
            .|.::|.:..|..||...|::..||   .:|:|.:|:.|:     |:.:.::.|:..|:.||||.
Mouse   304 HETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHLD-----YEDLGRLQYLSQVLKESLRL 363

  Fly   368 WTLAAATDRLCSKDYTLTDDDGTK-------LFDFKVGDRINIPISGLHLDDRYFPEPRKFDPDR 425
            :..|..|.||..::..:   ||.:       ||...|..|:          |.||.:|..|:|||
Mouse   364 YPPAWGTFRLLEEETLI---DGVRVPGNTPLLFSTYVMGRM----------DTYFEDPLTFNPDR 415

  Fly   426 FSEERKGDMVP---YTYLPFGVGPRNCIGNRYALMQVKGMLFNLLLHYKIEASP 476
            |     |...|   :||.||.:|.|:|||.::|.|:||.::..||...:....|
Mouse   416 F-----GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRIEFRLVP 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b2	NP_523646.1	CYP6-like	67..498	CDD:410679	109/451 (24%)
Cyp46a1	NP_034140.1	CYP46A1-like	61..484	CDD:410706	116/490 (24%)