Protein Alignment Cyp9b1 and ERG11

DIOPT Version :9

• Sequence 1: NP_523645.1
• Gene: Cyp9b1 / 35634
• FlyBaseID: FBgn0015038
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_011871.1
• Gene: ERG11 / 856398
• SGDID: S000001049
• Length: 530
• Species: Saccharomyces cerevisiae
• Alignment Length: 547
• Identity: 119/547 - (21%)
• Similarity: 185/547 - (33%)
• Gaps: 170/547 - (31%)

  Fly    16 LLFKWSTGTFKAFEGRNLYFEKPYPFL-------GNMAASALQKASFQKQISEFYNRTRHHKLVG 73
            |:|.|......|.    :|..|||.|.       |::.:..|     ..::...|...:.|:.|
Yeast    58 LVFYWIPWVGSAV----VYGMKPYEFFEECQKKYGDIFSFVL-----LGRVMTVYLGPKGHEFV- 112

  Fly    74 LFN--------------LRTPMIQINDPQLIKKICVKDFDHFPNHQTLNIPNERLVNDMLNVMRD 124
             ||              |.||:                   |......:.||.||:
Yeast   113 -FNAKLADVSAEAAYAHLTTPV-------------------FGKGVIYDCPNSRLM--------- 148

  Fly   125 QHWRNMRSVLTPVFTSAKMRNMFTLMNESFAQCLEHLKSSQPIAAGE--NAFELDMKVLCNKLSN 187
            :..:.::..||               .|:|       ||..|:.|.|  ..|........|:.:.
Yeast   149 EQKKFVKGALT---------------KEAF-------KSYVPLIAEEVYKYFRDSKNFRLNERTT 191

  Fly   188 ---DVIATTAFGLKVNSFDDPENEFHT-----IGKTLAFSRGLPFLKFMMCL---LAPKVFNFFK 241
               ||:.|           .||....|     :||.:.......|......|   ..|  .||
Yeast   192 GTIDVMVT-----------QPEMTIFTASRSLLGKEMRAKLDTDFAYLYSDLDKGFTP--INF-- 241

  Fly   242 LTIFDSTNVEYFVR----------LVVDAMQYREKHN-ITRPDMIQLLMEAKKESKD--NWTDDE 293
              :|.:..:|::.:          ..:..::.|.|:| |...|:|..||: ....||  ..||.|
Yeast   242 --VFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLMK-NSTYKDGVKMTDQE 303

  Fly   294 IVAQCFIFFFAAFENNSNLICTTAYELL---RNLDIQERLYEEVKETQEALKGAPLTYDAAQEMT 355
            | |...|......::.|  ..|:|:.||   ...|:|:.||||.....:..| ..||||..|||.
Yeast   304 I-ANLLIGVLMGGQHTS--AATSAWILLHLAERPDVQQELYEEQMRVLDGGK-KELTYDLLQEMP 364

  Fly   356 YMDMVISESLRKWTLSAAADRLCAKDYTLTDDEGTKLFEFKAGDNINIPICGLHWDERFFPQPQR 420
            .::..|.|:||......:..|...||..:.:..    :...||.::.:.....|..:.:||...:
Yeast   365 LLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTS----YVIPAGYHVLVSPGYTHLRDEYFPNAHQ 425

  Fly   421 FDPERFSERRKKDLIPYT-------------------YLPFGVGPRSCIGNRYAVMQAKGMLYNL 466
            |:..|::   |.....|:                   |||||.|...|||..:|..|. |:|.::
Yeast   426 FNIHRWN---KDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQL-GVLMSI 486

  Fly   467 MLNYKIEASPRTTRDMWESARGFNIIP 493
            .:        ||.:  |....|..:.|
Yeast   487 FI--------RTLK--WHYPEGKTVPP 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b1	NP_523645.1	p450	37..478	CDD:299894	109/509 (21%)
ERG11	NP_011871.1	CYP51-like	83..521	CDD:410668	110/518 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I1492
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1477
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050