DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp9b1 and CYP721A1

DIOPT Version :9

Sequence 1:	NP_523645.1	Gene:	Cyp9b1 / 35634	FlyBaseID:	FBgn0015038	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_177649.1	Gene:	CYP721A1 / 843850	AraportID:	AT1G75130	Length:	505	Species:	Arabidopsis thaliana

Alignment Length:	480	Identity:	115/480 - (23%)
Similarity:	201/480 - (41%)	Gaps:	65/480 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 TG-TFKAFEGRN-----LYFE---KPYPFLGNMAASALQKASFQKQISEFYNRTRHHKLVGLFNL 77
            || :::.|.|.:     |..|   ||.|...|......:.|....:.|..|.:|    .:..|..
plant    39 TGPSYRIFSGNSGEVSRLTAEAKSKPIPSGRNPHEFVHRVAPHYHEWSRVYGKT----FLYWFGS 99

  Fly    78 RTPMIQINDPQLIKKICVK--DFDHFPNHQTLNIPNERLVNDMLNVMRDQHWRNMRSVLTPVFTS 140
            : |::..:||:||::....  .||.. .|..|   ::.|....|..:|...|...|.:....||.
plant   100 K-PVVATSDPRLIREALTTGGSFDRI-GHNPL---SKLLYAQGLPGLRGDQWAFHRRIAKQAFTM 159

  Fly   141 AKMRNMFTLMNESFAQCLEHLKSSQPIAAGENAFELDMKVLCNKLSNDVIATTAFGLKVNSFDDP 205
            .|::.....|..|....:|   ..:.:..|....||::....:.||.::::.||||   ||.::.
plant   160 EKLKRWVPQMVTSTMMLME---KWEDMRNGGEEIELEVHKEMHNLSAEMLSRTAFG---NSVEEG 218

  Fly   206 ENEFHTIGKTLAFSRGLPFLKFMMCLLAPKVFNFFKLTIFDSTN-----VEYFVRLVVDAMQYRE 265
            :..|....:.:..     |......:..|. |.||.    ..||     :|..:|:.:..:....
plant   219 KGIFELQERMMRL-----FYLVRWSVYIPG-FRFFP----SKTNREIWRIEKQIRVSILKLIENN 273

  Fly   266 KHNITRP-DMIQLLMEA---KKESKDNWTDDEIVAQCFIFFFAAFENNSNLICTTAYELLRNLDI 326
            |..:.:. .::|..|..   :...::....:|:..:|..|:|||.|..:||:......|..|.:.
plant   274 KTAVEKSGTLLQAFMSPYTNQNGQEEKLGIEEVTDECKTFYFAAKETTANLMTFVLVLLAMNQEW 338

  Fly   327 QERLYEEV----KETQEALKGAPLTYDAAQEMTYMDMVISESLRKWTLSAAADRLCAKDYTLTDD 387
            |....|||    .:|     |.| |.|..|::..:.|:|:|:||.:..:...:|...|...|.|
plant   339 QNIAREEVICVLGQT-----GLP-TLDILQDLKTLSMIINETLRLYPPAMTLNRDTLKRAKLGD- 396

  Fly   388 EGTKLFEFKAGDNINIPICGLHWD-ERFFPQPQRFDPERFSERRKKDLIPYTYLPFGVGPRSCIG 451
                 .:..||..:.:.:..:|.| |.:....:.|:|.||.:.:|:..:   .:|||:|||:|:|
plant   397 -----LDIPAGTQLYLSVVAMHHDKETWGDDAEEFNPRRFEDPKKQSAL---LVPFGLGPRTCVG 453

  Fly   452 NRYAVMQAKGMLYNLMLNYKIEASP 476
            ...||.:||.:|..::..|....||
plant   454 QNLAVNEAKTVLATILKYYSFRLSP 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b1	NP_523645.1	p450	37..478	CDD:299894	109/456 (24%)
CYP721A1	NP_177649.1	p450	26..495	CDD:386267	115/480 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900