DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9b1 and CYP72A11

DIOPT Version :9

Sequence 1:	NP_523645.1	Gene:	Cyp9b1 / 35634	FlyBaseID:	FBgn0015038	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_188083.1	Gene:	CYP72A11 / 820693	AraportID:	AT3G14650	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	530	Identity:	122/530 - (23%)
Similarity:	222/530 - (41%)	Gaps:	99/530 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSFVEICLVLATIGLLLFKWSTGTFKAFEGRNL--YFEK------PY-PFLG------NMAASAL 50
            :|...:.:.:|.:.:..:.|.|..:..|:.:.|  |..:      || |.:|      :|.|.|.
plant     3 ISVASVTVSVAVVVVSWWVWRTLQWVWFKPKMLESYLRRQGLAGTPYTPLVGDLKKNFSMRAEAR 67

  Fly    51 QK------------ASFQKQISEFYNRTRHHKLVGLFNL--RTPMIQINDPQLIKKICVKDFDHF 101
            .|            ..:..|:.:.:.||       .|..  ..|.|.|.||:.|.::..|.:|..
plant    68 SKPINLTDDITPRIVPYPLQMLKTHGRT-------FFTWFGAIPTITIMDPEQITEVLNKVYDFQ 125

  Fly   102 PNHQTLNIPNERLV-NDMLNVMRDQHWRNMRSVLTPVFTSAKMRNMFTLMNESFAQCLEHLKSSQ 165
            ..|   ..|..||: ..:|:...|: |...|.::.|.|...|::||....::|.::.:  .|..:
plant   126 KAH---TFPLGRLIATGVLSYDGDK-WAKHRRIINPAFHLEKIKNMVPAFHQSCSEIV--CKWDK 184

  Fly   166 PIAAGENAFELDMKVLCNKLSNDVIATTAFGLKVNSFDDPENEF-----------HTIGKTLAFS 219
            .::..|::.|:|:......::.|||:.||||   :|..:.:..|           .|:.|  ||.
plant   185 LVSDKESSCEVDVWPGLVSMTADVISRTAFG---SSCVEGQRIFELQAELAQLIIQTVRK--AFI 244

  Fly   220 RGLPFLKFMMCLLAPKVFNFFKLTIFDSTNVEYFVRLVVD-AMQYREKHNITRPDMIQLLMEAK- 282
            .|..:|        |...|  :.....:..::..:|.:|: .::.||.......|::.:|:|:.
plant   245 PGYSYL--------PTKGN--RRMKAKAREIQVILRGIVNKRLRAREAGEAPNDDLLGILLESNL 299

  Fly   283 KESKDN-WTDDEIVAQCFIFFFAAFENNSNLICTTAYELLRNLDIQERLYEEVKET-----QEAL 341
            .::|.| .:.::::.:|.:|:|...|..|.|:..|...|.::.|.|.|..||||:.     .:|
plant   300 GQTKGNGMSTEDLMEECKLFYFVGQETTSVLLVWTMVLLSQHQDWQARAREEVKQVFGDKEPDA- 363

  Fly   342 KGAPLTYDAAQEMTYMDMVISESLRKWTLSAAADRLCAKDYTLTDDEGTKLFEFKAGDNINIPIC 406
                   :...::..|.|::.|.||.:.......|...|:..|.|      .....|..||:||.
plant   364 -------EGLNQLKVMTMILYEVLRLYPPIPQLSRAIHKEMELGD------LTLPGGVLINLPIL 415

  Fly   407 GLHWD-ERFFPQPQRFDPERF----SERRKKDLIPYTYLPFGVGPRSCIGNRYAVMQAKGMLYNL 466
            .:..| |.:......|.|:||    |:..|...   ::.||..|.|.|||..:|:::||..:..:
plant   416 LVQRDTELWGNDAGEFKPDRFKDGLSKATKNQA---SFFPFAWGSRICIGQNFALLEAKMAMALI 477

  Fly   467 MLNYKIEASP 476
            :..:..|.||
plant   478 LQRFSFELSP 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b1	NP_523645.1	p450	37..478	CDD:299894	115/492 (23%)
CYP72A11	NP_188083.1	p450	24..512	CDD:299894	119/509 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900