DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9b1 and Cyp4f1

DIOPT Version :9

Sequence 1:	NP_523645.1	Gene:	Cyp9b1 / 35634	FlyBaseID:	FBgn0015038	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_062569.2	Gene:	Cyp4f1 / 56266	RGDID:	70926	Length:	524	Species:	Rattus norvegicus

Alignment Length:	416	Identity:	105/416 - (25%)
Similarity:	167/416 - (40%)	Gaps:	60/416 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 VNDMLNVMRDQHWRNMRSVLTPVFTSAKMRNMFTLMNESFAQCLEHLKSSQPIAAGENAFELDMK 179
            :.|.|.|.....|...|.:|||.|....::....:.|:|  ..:.|.|..:.|:.|.:  .|||.
  Rat   132 LGDGLLVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDS--TNIMHAKWKRLISEGSS--RLDMF 192

  Fly   180 VLCNKLSNDVIATTAFGLKVNSFDD--PENEFHTIGKTLAFS-----RGLPFLKFMMCL--LAPK 235
            ...:.::.|.:....|     |||.  .|.....|...|..|     |....|.||..|  |.|.
  Rat   193 EHVSLMTLDSLQKCVF-----SFDSNCQEKSSEYIAAILELSALVAKRHQQPLLFMDLLYNLTPD 252

  Fly   236 VFNFFKLTIFDSTNVEYFVRLVVDAMQYREKHNITRP-----------------DMIQLLMEAKK 283
            ...|.|     :.|:   |....||: .||:.. |.|                 |.|.:|:..|.
  Rat   253 GMRFHK-----ACNL---VHEFTDAV-IRERRR-TLPDQGLDEFLKSKAKSKTLDFIDVLLLTKD 307

  Fly   284 ESKDNWTDDEIVAQCFIFFFAAFENNSNLICTTAYELLRNLDIQERLYEEVKETQEALKGAPLTY 348
            |.....:|::|.|:...|.|...:..::.:....|.|.::.:.|||..:||:|.........:.:
  Rat   308 EDGKELSDEDIRAEADTFMFEGHDTTASGLSWILYNLAKHPEYQERCRQEVQELLRDRDPEEIEW 372

  Fly   349 DAAQEMTYMDMVISESLRKWTLSAAADRLCAKDYTLTDDEGTKLFEFKAGDNINIPICGLHWDER 413
            |...::.::.|.|.||||.........|.|.:|..|.|..     ....|....|.|.|:|.:..
  Rat   373 DDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDILLPDGR-----TIPKGIICLISIFGIHHNPS 432

  Fly   414 FFPQPQRFDPERFSERRKKDLIPYTYLPFGVGPRSCIGNRYAVMQAKGMLYNLMLNYKI---EAS 475
            .:|.|:.::|.||.....||..|..::||..|||:|||..:|:.:.|..|...:|.:::   :..
  Rat   433 VWPDPEVYNPFRFDPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDDKE 497

  Fly   476 PRTTRDMWESARGFNIIPTTGFWMQL 501
            ||...::...|.|       |.|:::
  Rat   498 PRRQPELILRAEG-------GLWLRV 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b1	NP_523645.1	p450	37..478	CDD:299894	100/391 (26%)
Cyp4f1	NP_062569.2	CYP4F	74..515	CDD:410772	105/413 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900