DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9b1 and Cyp4ad1

DIOPT Version :9

Sequence 1:	NP_523645.1	Gene:	Cyp9b1 / 35634	FlyBaseID:	FBgn0015038	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_610380.1	Gene:	Cyp4ad1 / 35821	FlyBaseID:	FBgn0033292	Length:	516	Species:	Drosophila melanogaster

Alignment Length:	515	Identity:	110/515 - (21%)
Similarity:	207/515 - (40%)	Gaps:	90/515 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSFVEICLVLATI----GLLLFKW---STGTFKAFEGRNLYFEKPYPFLGNMAASALQKASFQKQ 58
            |..:.|.::||||    |:.:|.:   ..|..:...|     ..||||:||:....|:.|.:.|:
  Fly     1 MFLIAIAIILATILVFKGVRIFNYIDHMAGIMEMIPG-----PTPYPFVGNLFQFGLKPAEYPKK 60

  Fly    59 ISEFYNRTRHHKLVGLFNLRTPMIQINDPQLIKKICVKDFDHFPNHQTLNIPNERLVNDMLNVMR 123
            :.::..:........|..|:..|: ::||..|:.|.......:..|  |.......:.|.|....
  Fly    61 VLQYCRKYDFQGFRSLVFLQYHMM-LSDPAEIQNILSSSSLLYKEH--LYSFLRPWLGDGLLTSS 122

  Fly   124 DQHWRNMRSVLTPVFTSAKMRNMFTLMNES---FAQCLEHLKSSQPIAAGENAFELDMKVLCNKL 185
            ...|...:.:..|.|..:.:.....:::.:   |.|.|:.|..:|.:        .|.:.|..|.
  Fly   123 GARWLKHQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEV--------FDAQELVAKC 179

  Fly   186 SNDVIATTAFGLKVNSFDDPENEFHTIGKTLAFSRGLPFLKFMMC-LLAPKVFNFFKLTIFDSTN 249
            :.|::...|.|...:|.:...::.|...|.|             | ::..:.|:..|.  ||:
  Fly   180 TLDIVCENATGQDSSSLNGETSDLHGAIKDL-------------CDVVQERTFSIVKR--FDA-- 227

  Fly   250 VEYFVRLVVDAMQYREKHNITRPDM---------------------------IQLLMEAKKESKD 287
               ..||....|:.|...::.|.::                           :.:|:.||.:.|
  Fly   228 ---LFRLTSYYMKQRRALSLLRSELNRIISQRRHQLAAENTCQQGQPINKPFLDVLLTAKLDGK- 288

  Fly   288 NWTDDEIVAQCFIFFFAAFENNSNLICTTAYELLRNLDIQERLYEEVKETQEALKGAPLTYDA-- 350
            ...:.||:.:...|.|...:..:..|..|.|.|.|:.:||::..||    |..:.|.....:|
  Fly   289 VLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEE----QRRIFGENFAGEADL 349

  Fly   351 --AQEMTYMDMVISESLRKWTLSAAADRLCAKDYTLTDDEGTKLFEFKAGDNINIPICGLHWDER 413
              ..:|.|::::|.|:||   |..:...:...:....|..|||:.:.   ..:.:.:..:.::|:
  Fly   350 ARLDQMHYLELIIRETLR---LYPSVPLIARTNRNPIDINGTKVAKC---TTVIMCLIAMGYNEK 408

  Fly   414 FFPQPQRFDPERF-SERRKKDLIPYTYLPFGVGPRSCIGNRYAVMQAKGMLYNLMLNYKI 472
            :|..|..|.|||| :......:..:..:||..|||.||..::|:.|.|.:|..|:..::|
  Fly   409 YFDDPCTFRPERFENPTGNVGIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEI 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b1	NP_523645.1	p450	37..478	CDD:299894	100/472 (21%)
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	101/480 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900