DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9b1 and Cyp4f5

DIOPT Version :9

Sequence 1:	NP_523645.1	Gene:	Cyp9b1 / 35634	FlyBaseID:	FBgn0015038	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_775147.1	Gene:	Cyp4f5 / 286905	RGDID:	708364	Length:	526	Species:	Rattus norvegicus

Alignment Length:	448	Identity:	101/448 - (22%)
Similarity:	178/448 - (39%)	Gaps:	52/448 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 PMIQINDPQLIKKICVKDFDHFPNHQTLNIPNERLVNDMLNVMRDQHWRNMRSVLTPVFTSAKMR 144
            |::::.||..:..:........|...|.....:..:.|.|.:.....|...|.:|||.|....::
  Rat    97 PVLRLVDPAFVAPLLQAPALVAPKDTTFLRFLKPWLGDGLFLSSGDKWSRHRRLLTPAFHFDILK 161

  Fly   145 NMFTLMNESFAQCLEHLKSSQPIAAGENAFELDMKVLCNKLSNDVIATTAFGLKVNSFDDPENEF 209
            ....:.|:|..  :.|.|.......|....|:...:  :.::.|.:....||...|..:.|....
  Rat   162 PYVKIFNQSVN--IMHAKWKHLCLEGSARLEMFENI--SLMTLDSLQKCLFGFDSNCQESPSEYI 222

  Fly   210 HTIGK--TLAFSRG------LPFLKF---------MMCLLAPKVFNFFKLTI------FDSTNVE 251
            ..|.:  :|...|.      |.||.:         ..|.|   |.||....|      ..|...:
  Rat   223 SAILELSSLIIKRSQQLFLYLDFLYYRTADGRRFRKACDL---VHNFTDAVIRERRRLLSSQGTD 284

  Fly   252 YFVRLVVDAMQYREKHNITRPDMIQLLMEAKKESKDNWTDDEIVAQCFIFFFAAFENNSNLICTT 316
            .|       ::.:.|......|.|.:|:.||.|.....:|::|.|:...|.|...:..::.:...
  Rat   285 EF-------LESKTKSKSKTLDFIDVLLLAKDEHGKELSDEDIRAEADTFMFGGHDTTASALSWI 342

  Fly   317 AYELLRNLDIQERLYEEVKETQEALKGAPLTYDAAQEMTYMDMVISESLRKWTLSAAADRLCAKD 381
            .|.|.|:.:.|||..:||.|.....:...:.:|...::.::.|.|.||||....:....|.|.:|
  Rat   343 LYNLARHPEYQERCRQEVWELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPAIDLLRRCTQD 407

  Fly   382 YTLTDDEGTKLFEFKAGDNINIPICGLHWDERFFPQPQRFDPERFSERRKKDLIPYTYLPFGVGP 446
            ..|.|..     ....|:...|.|.|:|.:...:|.|:.|||.||....::...|.:::||..||
  Rat   408 IVLPDGR-----VIPKGNICVISIFGIHHNPSVWPDPEVFDPFRFDSENRQKRSPLSFIPFSAGP 467

  Fly   447 RSCIGNRYAVMQAKGMLYNLMLNYKI---EASPRTTRDMWESARGFNIIPTTGFWMQL 501
            |:|||..:|:.:.|.::...:|.:::   :..||...::...|.|       |.|:::
  Rat   468 RNCIGQTFAMNEMKVVVALTLLRFRVLPDDKEPRRKPEIILRAEG-------GLWLRM 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b1	NP_523645.1	p450	37..478	CDD:299894	96/423 (23%)
Cyp4f5	NP_775147.1	p450	52..516	CDD:278495	100/444 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900