Protein Alignment Cyp9b1 and Cyp3a23-3a1

DIOPT Version :10

• Sequence 1: NP_523645.1
• Gene: Cyp9b1 / 35634
• FlyBaseID: FBgn0015038
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 515
• Identity: 157/515 - (30%)
• Similarity: 264/515 - (51%)
• Gaps: 42/515 - (8%)

  Fly     4 VEICLVLATIGLLLFKWSTGTFKAFEGRNLYFEKPYPFLGNMAASALQKASFQKQISEFYNRTRH 68
            :|..::||.:.:||:.:.|.|...|:.:.:...||.||.|.:....:....|..:..:.|.
  Rat     9 LETWVLLAVVLVLLYGFGTRTHGLFKKQGIPGPKPLPFFGTVLNYYMGLWKFDVECHKKYG---- 69

  Fly    69 HKLVGLFNLRTPMIQINDPQLIKKICVKD-FDHFPNHQTLNIPNERLVNDMLNVMRDQHWRNMRS 132
             |:.|||:.:.|:..|.|.::||.:.||: |..|.|.:......  ::...::|.:|:.|:..|:
  Rat    70 -KIWGLFDGQMPLFAITDTEMIKNVLVKECFSVFTNRRDFGPVG--IMGKAISVSKDEEWKRYRA 131

  Fly   133 VLTPVFTSAKMRNMFTLMNESFAQCLEHLKSSQPIAAGENAFELDMKVLCNKLSNDVIATTAFGL 197
            :|:|.|||.:::.||.::.:.....:::|:.       |....:.:|.:....|.|||.:|:||:
  Rat   132 LLSPTFTSGRLKEMFPVIEQYGDILVKYLRQ-------EKGKPVPVKEVFGAYSMDVITSTSFGV 189

  Fly   198 KVNSFDDPENEFHTIGKTLA---FSRGLPFLKFMMCLLAPKVFNFFKLTIFDSTNVEYFVRLVVD 259
            .|:|.::|::.|....|.|.   |...| ||..::......|:....:.:|...::|:|.:.|..
  Rat   190 NVDSLNNPKDPFVEKAKKLLRIDFFDPL-FLSVVLFPFLTPVYEMLNICMFPKDSIEFFKKFVYR 253

  Fly   260 AMQYR----EKHNITRPDMIQLLMEAKKESKDN-----WTDDEIVAQCFIFFFAAFENNSNLICT 315
            ..:.|    :||   |.|.:||:|.|..:|||.     .:|.||.||..||.||.:|..|:.:..
  Rat   254 MKETRLDSVQKH---RVDFLQLMMNAHNDSKDKESHTALSDMEITAQSIIFIFAGYEPTSSTLSF 315

  Fly   316 TAYELLRNLDIQERLYEEVKETQEALKG-APLTYDAAQEMTYMDMVISESLRKWTLSAAADRLCA 379
            ..:.|..:.|.|::|.||:   ..||.. ||.|||...||.|:|||::|:||.:.:....:|:|.
  Rat   316 VLHSLATHPDTQKKLQEEI---DRALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERVCK 377

  Fly   380 KDYTLTDDEGTKLFEFKAGDNINIPICGLHWDERFFPQPQRFDPERFSERRKKDLIPYTYLPFGV 444
            ||..:..     :|..| |..:.||...||.|.:.:|:|:.|.|||||:..|..:.||.|||||.
  Rat   378 KDVEING-----VFMPK-GSVVMIPSYALHRDPQHWPEPEEFRPERFSKENKGSIDPYVYLPFGN 436

  Fly   445 GPRSCIGNRYAVMQAKGMLYNLMLNYKIEASPRTTRDMWESARGFNIIPTTGFWMQLVSR 504
            |||:|||.|:|:|..|..|..::.|:..:....|...:..|.:|. :.||....:::|.|
  Rat   437 GPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLSRQGL-LQPTKPIILKVVPR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b1	NP_523645.1	CYP6-like	67..498	CDD:410679	140/444 (32%)
Cyp3a23-3a1	NP_037237.2	CYP3A	67..491	CDD:410743	141/451 (31%)