Protein Alignment Cyp9b1 and Cyp3a18

DIOPT Version :9

• Sequence 1: NP_523645.1
• Gene: Cyp9b1 / 35634
• FlyBaseID: FBgn0015038
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_665725.2
• Gene: Cyp3a18 / 252931
• RGDID: 628709
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 486
• Identity: 147/486 - (30%)
• Similarity: 249/486 - (51%)
• Gaps: 34/486 - (6%)

  Fly     4 VEICLVLATIGLLLFKWSTGTFKAFEGRNLYFEKPYPFLGNMAASALQKASFQKQISEFYNRTRH 68
            :|..::|||..:|.:.:.|.:...|:...:...||.|..|.:.........|.....:.|.
  Rat     9 IETWVLLATSLMLFYIYGTYSHGLFKKLGIPGPKPVPLFGTIFNYGDGMWKFDDDCYKKYG---- 69

  Fly    69 HKLVGLFNLRTPMIQINDPQLIKKICVKD-FDHFPNHQTLNIPNERLVNDMLNVMRDQHWRNMRS 132
             |:.|.:....|.:.|.||::||.:.||: :..|.|.:......  .:...:.:..|:.|:.:|:
  Rat    70 -KIWGFYEGPQPFLAIMDPEIIKMVLVKECYSVFTNRRCFGPMG--FMKKAITMSEDEEWKRLRT 131

  Fly   133 VLTPVFTSAKMRNMFTLMNESFAQCLEHLKSSQPIAAGENAFELDMKVLCNKLSNDVIATTAFGL 197
            :|:|.|||.|::.||.||.:.....|::|:..:  |.||   .::||.:....|.|||..|:||:
  Rat   132 ILSPTFTSGKLKEMFPLMRQYGDTLLKNLRREE--AKGE---PINMKDIFGAYSMDVITGTSFGV 191

  Fly   198 KVNSFDDPENEF-HTIGKTLAFSRGLPFLKFMMCLLAP---KVFNFFKLTIFDSTNVEYFVRLVV 258
            .|:|.::|::.| ....|.|.|....|||  :..:|.|   .::.....:||...::.:|.:.|.
  Rat   192 NVDSLNNPQDPFVQKAKKILKFQIFDPFL--LSVVLFPFLTPIYEMLNFSIFPRQSMNFFKKFVK 254

  Fly   259 DAMQYR-EKHNITRPDMIQLLMEAK----KESKDNWTDDEIVAQCFIFFFAAFENNSNLICTTAY 318
            ...:.| :.:..:|.|.:||:|..:    :||:...:|.|:.||..||.|..::..|..|....|
  Rat   255 TMKKNRLDSNQKSRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAIIFIFGGYDATSTSISFIMY 319

  Fly   319 ELLRNLDIQERLYEEVKETQEALKG-APLTYDAAQEMTYMDMVISESLRKWTLSAAADRLCAKDY 382
            ||....::|::|..|:   ..||.. ||:||||..||.|:|||::||||.:.::...||:..||.
  Rat   320 ELATRPNVQKKLQNEI---DRALPNKAPVTYDALMEMEYLDMVVNESLRLYPIATRLDRVSKKDV 381

  Fly   383 TLTDDEGTKLFEFKAGDNINIPICGLHWDERFFPQPQRFDPERFSERRKKDLIPYTYLPFGVGPR 447
            .:..     :| ...|..:.|||..||.:..::.:|:.|:|||||:..|..:.||.|||||.|||
  Rat   382 EING-----VF-IPKGTVVTIPIYPLHRNPEYWLEPEEFNPERFSKENKGSIDPYVYLPFGNGPR 440

  Fly   448 SCIGNRYAVMQAKGMLYNLMLNYKIEASPRT 478
            :|||.|:|::..|..:..::.|:.|:...:|
  Rat   441 NCIGMRFALISMKLAVIGVLQNFNIQPCEKT 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b1	NP_523645.1	p450	37..478	CDD:299894	139/451 (31%)
Cyp3a18	NP_665725.2	CYP3A	67..492	CDD:410743	135/428 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1960
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm9060
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.770