Protein Alignment Cyp9b1 and CYP4A11

DIOPT Version :9

• Sequence 1: NP_523645.1
• Gene: Cyp9b1 / 35634
• FlyBaseID: FBgn0015038
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_000769.2
• Gene: CYP4A11 / 1579
• HGNCID: 2642
• Length: 519
• Species: Homo sapiens
• Alignment Length: 464
• Identity: 105/464 - (22%)
• Similarity: 173/464 - (37%)
• Gaps: 88/464 - (18%)

  Fly    50 LQKASFQKQISEFYNRTRHHKLVGLFNLRTPMIQINDPQLIKKICVKDFDHFPNHQTLNIPNERL 114
            ||:  .||.:..|.:...|....|...     :|:.||..:|.|..:.............|   .
Human    72 LQR--IQKWVETFPSACPHWLWGGKVR-----VQLYDPDYMKVILGRSDPKSHGSYRFLAP---W 126

  Fly   115 VNDMLNVMRDQHWRNMRSVLTPVFTSAKMRNMFTLMNESFAQCL----EHLKSSQPIAAGENAFE 175
            :...|.::..|.|...|.:|||.|....::....||.:|....|    |.|....|:...::.
Human   127 IGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHV-- 189

  Fly   176 LDMKVLCNKLSNDVIATTAFGLK------------VNSFDDPENEFHTIGKTLAFSRGLPFLKFM 228
                   :.::.|.|...||..:            :.:..|..|        |.|||
Human   190 -------SLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAISDLNN--------LVFSR-------- 231

  Fly   229 MCLLAPKVFNFFKL--TIFDST---------------NVEYFVRLVVDAMQYR-EKHNITRP--- 272
                   |.|.|..  ||:..|               :.:..::|....:|.. |...|.|.
Human   232 -------VRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEKIKRKRHL 289

  Fly   273 DMIQLLMEAKKESKDNWTDDEIVAQCFIFFFAAFENNSNLICTTAYELLRNLDIQERLYEEVKET 337
            |.:.:|:.||.|:....:|.::.|:...|.|...:..::.|....|.|..:...|||..||:...
Human   290 DFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSL 354

  Fly   338 QEALKGAPLTYDAAQEMTYMDMVISESLRKWTLSAAADRLCAKDYTLTDDEGTKLFEFKAGDNIN 402
            ..  .||.:|::...:|.|..|.|.|:||.:.......|..:...|..|  |..|   ..|..:.
Human   355 LG--DGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD--GRSL---PKGIMVL 412

  Fly   403 IPICGLHWDERFFPQPQRFDPERFSERRKKDLIPYTYLPFGVGPRSCIGNRYAVMQAKGMLYNLM 467
            :.|.|||.:.:.:|.|:.|||.||:....:.  .:.:|||..|.|:|||.::|:.:.|......:
Human   413 LSIYGLHHNPKVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATALTL 475

  Fly   468 LNYKIEASP 476
            |.:::...|
Human   476 LRFELLPDP 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b1	NP_523645.1	p450	37..478	CDD:299894	105/464 (23%)
CYP4A11	NP_000769.2	p450	52..505	CDD:278495	105/464 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900