Protein Alignment Cyp9b1 and Cyp3a11

DIOPT Version :10

• Sequence 1: NP_523645.1
• Gene: Cyp9b1 / 35634
• FlyBaseID: FBgn0015038
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Alignment Length: 525
• Identity: 164/525 - (31%)
• Similarity: 272/525 - (51%)
• Gaps: 60/525 - (11%)

  Fly     4 VEICLVLATIGLLLFKWSTGTFKAFEGRNLYFEKPYPFLGNMAASALQKASFQKQISEF----YN 64
            :|..::||...:||:::.|...:.|:.:.:...||.||||.:       .::.|.:.:|    |.
Mouse     9 LETWVLLAISLVLLYRYGTRKHELFKKQGIPGPKPLPFLGTV-------LNYYKGLWKFDMECYK 66

  Fly    65 RTRHHKLVGLFNLRTPMIQINDPQLIKKICVKD-FDHFPNHQTLNIPNERLVNDMLNVMRDQHWR 128
              ::.|..|||:.:||::.:.||:.||.:.||: |..|.|.:......  :::..:::.:|..|:
Mouse    67 --KYGKTWGLFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRDFGPVG--IMSKAISISKDDEWK 127

  Fly   129 NMRSVLTPVFTSAKMRNMFTLMNESFAQCL-----EHLKSSQPIAAGENAFELDMKVLCNKLSND 188
            ..|::|:|.|||.|::.||.:: |.:...|     :..|..:|:.         ||.:....|.|
Mouse   128 RYRALLSPTFTSGKLKEMFPVI-EQYGDILVKYLRQKAKKGKPVT---------MKDVLGAYSMD 182

  Fly   189 VIATTAFGLKVNSFDDPENEFHTIGKTLA---FSRGLPFLKFMMCLLAPKVFNFFKLTIFDSTNV 250
            ||.:|:||:.|:|.::||:.|....|.|.   |...|.|...:...|.| |:....:.:|...::
Mouse   183 VITSTSFGVNVDSLNNPEDPFVEKAKKLLRFDFFDPLLFSVVLFPFLTP-VYEMLNICMFPKDSI 246

  Fly   251 EYFVRLVVDAMQ-----YREKHNITRPDMIQLLMEAKKESKDN-----WTDDEIVAQCFIFFFAA 305
            |:|.:. ||.|:     .::||   |.|.:||:|.:...|||.     .:|.||.||..||.||.
Mouse   247 EFFKKF-VDRMKESRLDSKQKH---RVDFLQLMMNSHNNSKDKVSHKALSDMEITAQSIIFIFAG 307

  Fly   306 FENNSNLICTTAYELLRNLDIQERLYEEVKETQEALKG-APLTYDAAQEMTYMDMVISESLRKWT 369
            :|..|:.:..|.:.|..:.|||::|.:|:   .|||.. ||.|||...||.|:|||::|:||.:.
Mouse   308 YETTSSTLSFTLHSLATHPDIQKKLQDEI---DEALPNKAPPTYDTVMEMEYLDMVLNETLRLYP 369

  Fly   370 LSAAADRLCAKDYTLTDDEGTKLFEFKAGDNINIPICGLHWDERFFPQPQRFDPERFSERRKKDL 434
            ::...:|:|.||..|   .|..:   ..|..:.||...||.|.:.:.:|:.|.|||||:..|..:
Mouse   370 IANRLERVCKKDVEL---NGVYI---PKGSTVMIPSYALHHDPQHWSEPEEFQPERFSKENKGSI 428

  Fly   435 IPYTYLPFGVGPRSCIGNRYAVMQAKGMLYNLMLNYKIEASPRTTRDMWESARGFNIIPTTGFWM 499
            .||.|||||.|||:|:|.|:|:|..|..|..:|.|:..:....|...:..|.:|. :.|.....:
Mouse   429 DPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKLSRQGL-LQPEKPIVL 492

  Fly   500 QLVSR 504
            ::|.|
Mouse   493 KVVPR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b1	NP_523645.1	CYP6-like	67..498	CDD:410679	146/450 (32%)
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	146/452 (32%)