Protein Alignment Cyp9b1 and CYP3A7-CYP3A51P

DIOPT Version :9

• Sequence 1: NP_523645.1
• Gene: Cyp9b1 / 35634
• FlyBaseID: FBgn0015038
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001243426.2
• Gene: CYP3A7-CYP3A51P / 100861540
• HGNCID: 51504
• Length: 535
• Species: Homo sapiens
• Alignment Length: 499
• Identity: 157/499 - (31%)
• Similarity: 268/499 - (53%)
• Gaps: 60/499 - (12%)

  Fly     4 VEICLVLATIGLLLFKWSTGTFKAFEGRNLYFEKPYPFLGNMAASALQKASFQKQI----SEFYN 64
            ||..|:||...:||:.:.|.|...|:...:....|.|||||    ||   ||:|..    .|.|.
Human     9 VETWLLLAVSLILLYLYGTRTHGLFKKLGIPGPTPLPFLGN----AL---SFRKGYWTFDMECYK 66

  Fly    65 RTRHHKLVGLFNLRTPMIQINDPQLIKKICVKD-FDHFPNHQTLNIPNERLVNDMLNVMRDQHWR 128
            :.|  |:.|:::.:.||:.|.||.:||.:.||: :..|.|.:......  .:.:.:::..|:.|:
Human    67 KYR--KVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRRPFGPVG--FMKNAISIAEDEEWK 127

  Fly   129 NMRSVLTPVFTSAKMRNMFTLMNESFAQCLEHLKSSQPIAAGENAFELDMKVLCNKLSNDVIATT 193
            .:||:|:|.|||.|::.|..::.:.....:.:|:..     .|....:.:|.:....|.|||.:|
Human   128 RIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRE-----AETGKPVTLKHVFGAYSMDVITST 187

  Fly   194 AFGLKVNSFDDPENEF-HTIGKTLAFSRGLPFLKFMMCLLAPKVFNFFKLT-IFDSTNVEYFVRL 256
            :||:.::|.::|::.| ....|.|.|:...||      :|:.|||.|  || |.::.|:..|.|.
Human   188 SFGVSIDSLNNPQDPFVENTKKLLRFNPLDPF------VLSIKVFPF--LTPILEALNITVFPRK 244

  Fly   257 VVDAM-----QYRE-------KHNITRPDMIQLLMEAKKESKDNWT-----DDEIVAQCFIFFFA 304
            |:..:     |.:|       ||   |.|.:||:::: :.|||:.|     |.|::||..||.||
Human   245 VISFLTKSVKQIKEGRLKETQKH---RVDFLQLMIDS-QNSKDSETHKALSDLELMAQSIIFIFA 305

  Fly   305 AFENNSNLICTTAYELLRNLDIQERLYEEVKETQEALKGAPLTYDAAQEMTYMDMVISESLRKWT 369
            .:|..|:::....|||..:.|:|:::.:|: :|....| ||.|||...::.|:|||::|:||.:.
Human   306 GYETTSSVLSFIIYELATHPDVQQKVQKEI-DTVLPNK-APPTYDTVLQLEYLDMVVNETLRLFP 368

  Fly   370 LSAAADRLCAKDYTLTDDEGTKLFEFKAGDNINIPICGLHWDERFFPQPQRFDPERFSERRKKDL 434
            ::...:|:|.||..:..     :| ...|..:.||...||.|.:::.:|::|.|||||::.|.::
Human   369 VAMRLERVCKKDVEING-----MF-IPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNI 427

  Fly   435 IPYTYLPFGVGPRSCIGNRYAVMQAKGMLYNLMLNYKIEASPRT 478
            .||.|.|||.|||:|||.|:|::..|..|..::.|:..:....|
Human   428 DPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKET 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b1	NP_523645.1	p450	37..478	CDD:299894	146/464 (31%)
CYP3A7-CYP3A51P	NP_001243426.2	p450	39..492	CDD:278495	147/469 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	262	1.000	Domainoid score	I1946
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	277	1.000	Inparanoid score	I2940
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.770