DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9b1 and tbxas1

DIOPT Version :9

Sequence 1:	NP_523645.1	Gene:	Cyp9b1 / 35634	FlyBaseID:	FBgn0015038	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	XP_031753608.1	Gene:	tbxas1 / 100327243	XenbaseID:	XB-GENE-994325	Length:	532	Species:	Xenopus tropicalis

Alignment Length:	561	Identity:	163/561 - (29%)
Similarity:	267/561 - (47%)	Gaps:	102/561 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VEICLVLATIGLLLFKWSTGTFKAFEGRNLYFEKPYPFLGNMAASALQKASFQKQISEFYNRTRH 68
            |.:.||...:| ||:.:|...|...|...:...||.||:||:..       |||   .|:...||
Frog    14 VTLTLVAGFLG-LLYWYSVSAFWQLEKAGIKHPKPLPFIGNIML-------FQK---GFWEGDRH 67

  Fly    69 -----HKLVGLFNLRTPMIQINDPQLIKKICVKDFDHFPNH-QTLNIPNERLVNDMLNVMRDQHW 127
                 ..:.|.:..|.|||.|.:|..||::..|||.:|.|. |.||:..:.: :|.|..:||..|
Frog    68 LLKTYGPICGYYMGRRPMIVIAEPDAIKQVLQKDFVNFTNRMQRLNLVTKPM-SDSLLCLRDDKW 131

  Fly   128 RNMRSVLTPVFTSAKMRNMFTLMNESFAQCLEHL-KSSQPIAAGENAFELDMKVLCNKLSNDVIA 191
            :.:||||||.|::|:|:.|..|:|    ||.:.| ::....|:...|..:.....|  .:.||:|
Frog   132 KRVRSVLTPSFSAARMKEMCPLIN----QCCDVLVENLMEYASSGEACNVQRCYAC--FTMDVVA 190

  Fly   192 TTAFGLKVNSFDDPEN----------EFHTIGKTLAFSRGLPFLKFMMCLLAPKVF--------N 238
            :.|||.:|:|..|.::          |..|..|.:.          ::||..|.:.        |
Frog   191 SVAFGTQVDSQRDSDHPLVQNCKRFLELFTPFKPVV----------LLCLAFPSIMIPIARRLPN 245

  Fly   239 FFKLTIFDSTNVEYFVRLVVDAMQYREKH--NITRPDMIQLLMEA-------------------- 281
            ..:    |..| .:|::::.|.:.:||..  |..|.|.:||:::|
Frog   246 KHR----DRIN-SFFLKVIRDIIAFRENQPPNERRRDFLQLMLDARDSAGHVSVDHFDIVNQADL 305

  Fly   282 -------------KKESKDNWTDDEIVAQCFIFFFAAFENNSNLICTTAYELLRNLDIQERLYEE 333
                         :|.::....::||:.|.|||..|.:|...:|:...:|.|..:.|.||:|.:|
Frog   306 SVPQNQDRGQDPPRKSTQKTLNEEEILGQAFIFLIAGYETTCSLLSFASYLLATHPDCQEKLLKE 370

  Fly   334 VKETQEALKGAPLTYDAAQEMTYMDMVISESLRKWTLSAAADRLCAKDYTLTDDEGTKLFEFKAG 398
            |.|..:..:.|  .|:...::.||:|||:|:||.:..:....|..|:|.|:..      ....||
Frog   371 VDEFSQEHEEA--DYNTVHDLPYMEMVINETLRMYPPAYRFAREAARDCTVMG------LGIPAG 427

  Fly   399 DNINIPICGLHWDERFFPQPQRFDPERFSERRKKDLIPYTYLPFGVGPRSCIGNRYAVMQAKGML 463
            ..:.|||..|..|.||:.:|::|:||||:...|:...|:.:||||.|||||||.|.|:::||..|
Frog   428 AVVEIPIGCLQNDPRFWHEPEKFNPERFTAEEKQKRHPFLFLPFGAGPRSCIGMRLALLEAKITL 492

  Fly   464 YNLMLNYKIEASPRTTRDMWESARGFNIIPTTGFWMQLVSR 504
            |.::..::.:....|...:..||. ..:.|..|.::::|:|
Frog   493 YRVLRKFRFQTCDLTQIPLQLSAM-TTLRPKDGVYVRVVAR 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9b1	NP_523645.1	p450	37..478	CDD:299894	147/500 (29%)
tbxas1	XP_031753608.1	cytochrome_P450	71..526	CDD:425388	140/485 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010