DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42Er and Cd63

DIOPT Version :9

Sequence 1:NP_523644.1 Gene:Tsp42Er / 35629 FlyBaseID:FBgn0033139 Length:211 Species:Drosophila melanogaster
Sequence 2:NP_001036045.1 Gene:Cd63 / 12512 MGIID:99529 Length:238 Species:Mus musculus


Alignment Length:225 Identity:63/225 - (28%)
Similarity:103/225 - (45%) Gaps:31/225 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 LMIRYLAFLFNFLCAV----LGIATIVVNVIAIDQIAPKDQLILGLYIAVGSIVFLLSFFGCFGA 66
            |.:..|||.   .|||    :|:|..||...||........|:..:.||||:.:||::|.||.||
Mouse    14 LYVLLLAFC---ACAVGLIAIGVAVQVVLKQAITHETTAGSLLPVVIIAVGAFLFLVAFVGCCGA 75

  Fly    67 IKESIC--VTWAYATSMLVMLIVSIVML-FVFRMHFEED---SITKLKQAFAKQTNTFDAMAEYQ 125
            .||:.|  :|:|...|:::::.|::.:. :|||...:.:   |..:..|.:.|...|...:.:.|
Mouse    76 CKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFNKSFQQQMQNYLKDNKTATILDKLQ 140

  Fly   126 TQYQCCGIYKLKDY----GDAYITVPSSCYDQ------ND----TPYRDGCLAKMETQYEE--LL 174
            .:..|||.....|:    |.|...||.||...      ||    |.:..||:..:.....:  ||
Mouse   141 KENNCCGASNYTDWENIPGMAKDRVPDSCCINITVGCGNDFKESTIHTQGCVETIAIWLRKNILL 205

  Fly   175 KGPKIVGWMLMVIEIGAFTFSTIMGVSLRN 204
            .....:|  :..:|:....||..:..|:|:
Mouse   206 VAAAALG--IAFVEVLGIIFSCCLVKSIRS 233

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42ErNP_523644.1 Tetraspannin 8..195 CDD:278750 58/212 (27%)
tetraspanin_LEL 93..174 CDD:239401 23/99 (23%)
Cd63NP_001036045.1 Tetraspannin 10..227 CDD:395265 61/217 (28%)
CD63_LEL 105..203 CDD:239419 23/97 (24%)
Lysosomal targeting motif. /evidence=ECO:0000269|PubMed:21041449 234..238 63/225 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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