Protein Alignment Tsp42Er and Cd63

DIOPT Version :10

• Sequence 1: NP_523644.1
• Gene: Tsp42Er / 35629
• FlyBaseID: FBgn0033139
• Length: 211
• Species: Drosophila melanogaster
• Sequence 2: NP_031679.1
• Gene: Cd63 / 12512
• MGIID: 99529
• Length: 238
• Species: Mus musculus
• Alignment Length: 225
• Identity: 63/225 - (28%)
• Similarity: 103/225 - (45%)
• Gaps: 31/225 - (13%)

  Fly     6 LMIRYLAFLFNFLCAV----LGIATIVVNVIAIDQIAPKDQLILGLYIAVGSIVFLLSFFGCFGA 66
            |.:..|||.   .|||    :|:|..||...||........|:..:.||||:.:||::|.||.||
Mouse    14 LYVLLLAFC---ACAVGLIAIGVAVQVVLKQAITHETTAGSLLPVVIIAVGAFLFLVAFVGCCGA 75

  Fly    67 IKESIC--VTWAYATSMLVMLIVSIVML-FVFRMHFEED---SITKLKQAFAKQTNTFDAMAEYQ 125
            .||:.|  :|:|...|:::::.|::.:. :|||...:.:   |..:..|.:.|...|...:.:.|
Mouse    76 CKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFNKSFQQQMQNYLKDNKTATILDKLQ 140

  Fly   126 TQYQCCGIYKLKDY----GDAYITVPSSCYDQ------ND----TPYRDGCLAKMETQYEE--LL 174
            .:..|||.....|:    |.|...||.||...      ||    |.:..||:..:.....:  ||
Mouse   141 KENNCCGASNYTDWENIPGMAKDRVPDSCCINITVGCGNDFKESTIHTQGCVETIAIWLRKNILL 205

  Fly   175 KGPKIVGWMLMVIEIGAFTFSTIMGVSLRN 204
            .....:|  :..:|:....||..:..|:|:
Mouse   206 VAAAALG--IAFVEVLGIIFSCCLVKSIRS 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Er	NP_523644.1	Tetraspanin	8..195	CDD:459767	58/212 (27%)
Cd63	NP_031679.1	Tetraspanin	10..229	CDD:459767	61/219 (28%)
		CD63_LEL	105..203	CDD:239419	23/97 (24%)
		Lysosomal targeting motif. /evidence=ECO:0000269|PubMed:21041449	234..238		63/225 (28%)