Protein Alignment Tsp42Eq and CD63

DIOPT Version :9

• Sequence 1: NP_523643.2
• Gene: Tsp42Eq / 35628
• FlyBaseID: FBgn0033138
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_001244318.1
• Gene: CD63 / 967
• HGNCID: 1692
• Length: 238
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 57/246 - (23%)
• Similarity: 96/246 - (39%)
• Gaps: 56/246 - (22%)

  Fly     4 GTKALKVSSFVLDFLCCVLAALTIAACSYALIAFSHSV------AIRVPSILGIVLGGLLFFSTI 62
            |.|.:|...:||....|..|...||....|.:..|.::      ...:|.:: |.:|..||....
Human     6 GMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVI-IAVGVFLFLVAF 69

  Fly    63 FGCIAALRESIRMTWIYAAILLALVFSQITVILAQPINYELLANETIYDAWQGQL------YHS- 120
            .||..|.:|:..:...:|..|..::..::...:|..:..:.:.:| ..:.::.|:      .|:
Human    70 VGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSE-FNNNFRQQMENYPKNNHTA 133

  Fly   121 ---DRMSYFEIKYHCCGQTGPANYPD-------SGLVIPQSCYFNQNATVTTDLYTVGC--NHQL 173
               |||   :..:.||   |.|||.|       |...:|.||..|         .||||  |...
Human   134 SILDRM---QADFKCC---GAANYTDWEKIPSMSKNRVPDSCCIN---------VTVGCGINFNE 183

  Fly   174 AAAFVKGTRWEKITDW-------------SVVGVEILTVIIAGLLAITLQN 211
            .|...:|. .|||..|             .:..||:|.::.|..|..::::
Human   184 KAIHKEGC-VEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIRS 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eq	NP_523643.2	Tetraspannin	8..209	CDD:278750	55/238 (23%)
		tetraspanin_LEL	95..173	CDD:239401	24/96 (25%)
CD63	NP_001244318.1	Tetraspannin	10..227	CDD:395265	54/234 (23%)
		CD63_LEL	105..203	CDD:239419	29/114 (25%)
		Lysosomal targeting motif. /evidence=ECO:0000250|UniProtKB:P41731	234..238		57/246 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810