Protein Alignment Pgant3 and galnt4

DIOPT Version :10

• Sequence 1: NP_610256.1
• Gene: Pgant3 / 35627
• FlyBaseID: FBgn0027558
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001072705.1
• Gene: galnt4 / 780162
• XenbaseID: XB-GENE-5803663
• Length: 582
• Species: Xenopus tropicalis
• Alignment Length: 683
• Identity: 234/683 - (34%)
• Similarity: 318/683 - (46%)
• Gaps: 144/683 - (21%)

  Fly     8 LKKLWLLYLFLLFFAFFMFAISINLYVASIQGG-----------------DAEMRHP---KPPPK 52
            :|...:|..|::  |:.:...|..::..|:..|                 :.|:|.|   ||||
 Frog    12 VKTCTVLGFFMI--AYILVEFSSPVFHTSVNEGLTTKRRWERVITLAEEKNEELRQPVYKKPPP- 73

  Fly    53 RRSLWPHKNIVAHYIGKGDIFGNMTADDYNINLFQPINGEGADGRPVVVPPRDRFRMQRFFRLNS 117
                                       |.|      :.||......:.:.|.::..........:
 Frog    74 ---------------------------DPN------MPGEWGKAARLELGPTEKKMQDESIEKYA 105

  Fly   118 FNLLASDRIPLNRTLKDYRTPECRDKKY-ASGLPSTSVIIVFHNEAWSVLLRTITSVINRSPRHL 181
            .|:..||:|.|:|.:.|.|..||:.|.: ...||:|||:|.|:|||.|.|||||.||:..||..|
 Frog   106 LNIYLSDQISLHRHIMDNRMYECKSKTFNYRKLPTTSVVIAFYNEALSTLLRTIHSVLETSPAVL 170

  Fly   182 LKEIILVDDASDRSYLKRQLESYVKVLAVPTRIFRMKKRSGLVPARLLGAENARGDVLTFLDAHC 246
            |:|||||||.||:.|||.|||.|:..|. ..|:.|..||.|||.||::||..|.||||||||.||
 Frog   171 LREIILVDDFSDKVYLKSQLEDYIGGLD-RVRLIRTTKREGLVRARIIGATYAIGDVLTFLDCHC 234

  Fly   247 ECSRGWLEPLLSRIKESRKVVICPVIDIISDDNFS-YTKTFENHWGAFNWQLSFRWFS-SDRKRQ 309
            ||..|||||||.||.|:...|:|||||.|..:.|. |.:|.|...|.|:|:|:|:|.: .:::||
 Frog   235 ECISGWLEPLLQRIGENETAVVCPVIDTIDWNTFEFYMQTGEPMIGGFDWRLTFQWHAVPEKERQ 299

  Fly   310 TAGNSSKDSTDPIATPGMAGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGGRVEISP 374
                ..|...|||.:|.|||||||:.:|||..:|:||..|.||||||:|:|||:|||||.:||.|
 Frog   300 ----RRKSRIDPIRSPTMAGGLFAVSKKYFEYLGTYDMGMEVWGGENLELSFRVWQCGGTLEIEP 360

  Fly   375 CSHVGHVFRSSTPYTFPGGMSEVLTDNLARAATVWMDDWQYFIMLYTSGLTLGAKDKVNVTERVA 439
            ||||||||....||..|.     ...|.||||.||||.  |..:.|........::..:::||..
 Frog   361 CSHVGHVFPKKAPYARPN-----FLQNTARAAEVWMDG--YKELFYNRNPPARKENYGDISERKL 418

  Fly   440 LRERLQCKPFSWYLENIWPEHFFPAPDR--FFGKIIWLDGETECAQAYSKHMKNLPGRALSREWK 502
            ||||||||.|.|||:|::|:...| .||  :.|.:..:....||.. |:....|..|..||
 Frog   419 LRERLQCKSFDWYLKNVFPDLHIP-EDRPGWHGAVRSMGISNECLD-YNAPDHNPTGAHLS---- 477

  Fly   503 RAFEEIDSKAEELMALIDLERDKCLRPLKEDVPRSSLSAVTVGDCTSHAQSMDMFV-ITPKGQIM 566
                                                     :..|  |.|..:.|. .|...:|.
 Frog   478 -----------------------------------------LFGC--HGQGGNQFFEYTTMREIR 499

  Fly   567 TND--NVCLTYRQQK--LGVIKMLKNRNATTSNVMLAQCASDSSQLWTYDMDTQQISHRDTKLCL 627
            .|.  .:|....:|:  :|::...|:.|....|:           .|.:..| ..|.|..:..|:
 Frog   500 FNSVTELCAEVPEQQTYIGMMHCPKDGNPVPKNI-----------AWEFRND-GTIYHPSSGTCI 552

  Fly   628 TLKAATNSRLQKVEKVVLSMECDFKDITQKWGF 660
            :....:..|..     |....||..|..|.|.|
 Frog   553 SSYRTSEGRAD-----VQMKGCDPSDKNQLWKF 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	pp-GalNAc-T	153..457	CDD:133004	163/305 (53%)
		beta-trefoil_Ricin_Pgant3-like	515..661	CDD:467338	26/151 (17%)
galnt4	NP_001072705.1	pp-GalNAc-T	142..436	CDD:133004	163/305 (53%)
		beta-trefoil_Ricin-like	446..581	CDD:483949	34/200 (17%)