DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant3 and galnt16

DIOPT Version :9

Sequence 1:	NP_610256.1	Gene:	Pgant3 / 35627	FlyBaseID:	FBgn0027558	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	NP_001039091.1	Gene:	galnt16 / 733908	XenbaseID:	XB-GENE-986567	Length:	562	Species:	Xenopus tropicalis

Alignment Length:	559	Identity:	192/559 - (34%)
Similarity:	269/559 - (48%)	Gaps:	108/559 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 FRLNSFNLLASDRIPLNRTLKDYRTPECRDKKYASGLPSTSVIIVFHNEAWSVLLRTITSVINRS 177
            :|.::||.|.||::...|.::|.|...|....:.:.||||||||.|||||.|.|||||.||:.||
Frog    93 YRQHAFNQLESDKLSSERPIRDTRHYRCTSVHHDNDLPSTSVIITFHNEARSTLLRTIKSVLIRS 157

  Fly   178 PRHLLKEIILVDDASDRSYLKRQLESYVKVLAVPTRIFRMKKRSGLVPARLLGAENARGDVLTFL 242
            |.:|::|||||||.|......:.|....||     :..|..:|.||:.:|:.|||.|...|||||
Frog   158 PGNLIQEIILVDDFSTDPDDCQLLTKIPKV-----KCLRNNRREGLIRSRVRGAELAAAPVLTFL 217

  Fly   243 DAHCECSRGWLEPLLSRIKESRKVVICPVIDIISDDNFSYTKTFENHWGAFNWQLSFRWFSSDRK 307
            |:|||.:..||:|||.|:|:....|:.|:||:||.|||:|.....:..|.|:|.|.|:|.....:
Frog   218 DSHCEVNNEWLQPLLQRVKDDHTRVVSPIIDVISLDNFAYLAASADLRGGFDWSLHFKWEQIPIE 282

  Fly   308 RQTAGNSSKDSTDPIATPGMAGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGGRVEI 372
            ::.   |..|.|..|.||.:|||:|.||:.:|.::|.||:.|.:|||||.|:|||:|.|||.:||
Frog   283 QKM---SRTDPTSSIRTPVIAGGIFVIDKSWFNQLGKYDTQMDIWGGENFELSFRVWMCGGSLEI 344

  Fly   373 SPCSHVGHVFRSSTPYTFPGGMSEVLTDNLARAATVWMDDW-QYFIMLYTSGLTLGAKDKVNVTE 436
            .|||.||||||...||.||.|.:.....|..|...||||:: ||:.....|.:   .|...:|.:
Frog   345 VPCSRVGHVFRKRHPYEFPDGNALTYIKNTKRTVEVWMDEYKQYYYQARPSAI---GKSYGSVAD 406

  Fly   437 RVALRERLQCKPFSWYLENIWPEHFFPAPDRFFGKIIWLDGETECAQAYSKHMK-NLPGRALSRE 500
            ||.||::|.||.|.|||:|::||...|..:...| :|...|  .|.::.::... |:|
Frog   407 RVELRKKLSCKSFQWYLQNVYPELKIPEKEVISG-LIKQGG--NCMESQTRDTTGNIP------- 461

  Fly   501 WKRAFEEIDSKAEELMALIDLERDKCLRPLKEDVPRSSLSAVTVGDCTSHAQSMDMFVITPKGQ- 564
                                                     |.:..|...|.|      .|..|
Frog   462 -----------------------------------------VMLTQCKGSANS------APAAQE 479

  Fly   565 ------IMTNDNVCLTYRQQKLGVIKMLKNRNATTSNVMLAQC-ASDSSQLWTYDMDTQQISHRD 622
                  ::...:.|||......|.:            |||..| ..||.|.|  .:....:.|..
Frog   480 WALSENVIKQQDRCLTISSFSTGAL------------VMLEPCNQKDSRQKW--KLKGHFLQHIG 530

  Fly   623 TKLCL---TLKAATNSRLQKVEKVVLSMECDFKDITQKW 658
            :.|||   :.:|..|             .|....::|:|
Frog   531 SALCLDTHSTRAVIN-------------PCQSDLLSQQW 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	Glyco_tranf_2_3	150..386	CDD:290369	117/235 (50%)
		pp-GalNAc-T	153..457	CDD:133004	142/304 (47%)
		Ricin_B_lectin	516..658	CDD:279046	26/152 (17%)
		RICIN	524..660	CDD:238092	27/146 (18%)
galnt16	NP_001039091.1	pp-GalNAc-T	133..427	CDD:133004	142/304 (47%)
galnt16	NP_001039091.1	Ricin_B_lectin	439..556	CDD:366226	32/200 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010