Protein Alignment Pgant3 and galnt1

DIOPT Version :10

• Sequence 1: NP_610256.1
• Gene: Pgant3 / 35627
• FlyBaseID: FBgn0027558
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: XP_031759269.1
• Gene: galnt1 / 594943
• XenbaseID: XB-GENE-1013398
• Length: 559
• Species: Xenopus tropicalis
• Alignment Length: 587
• Identity: 252/587 - (42%)
• Similarity: 348/587 - (59%)
• Gaps: 91/587 - (15%)

  Fly    79 DDYNINLFQPINGEGADGRPVVVPPRDRFRMQRFFRLNSFNLLASDRIPLNRTLKDYRTPECRDK 143
            |..:||. :|..|.|..|:|||:|..::.:|:..|::|.|||:||:.|.|||:|.|.|...|:.|
 Frog    46 DGPDINQ-KPHEGPGEMGKPVVIPKEEQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTK 109

  Fly   144 KYASGLPSTSVIIVFHNEAWSVLLRTITSVINRSPRHLLKEIILVDDASDRSYLKRQLESYVKVL 208
            .|...||:|||:||||||||:.||||:.|||||||||||:|||||||||:|.:|||.||:|||.|
 Frog   110 VYPDSLPTTSVVIVFHNEAWTTLLRTVHSVINRSPRHLLQEIILVDDASEREFLKRPLETYVKKL 174

  Fly   209 AVPTRIFRMKKRSGLVPARLLGAENARGDVLTFLDAHCECSRGWLEPLLSRIKESRKVVICPVID 273
            .||..:.||::||||:.|||.||..::|.|:|||||||||:.|||||||:|||..|:.|:||:||
 Frog   175 TVPVHVLRMEQRSGLIRARLRGAAASKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIID 239

  Fly   274 IISDDNFSYTKTFENHWGAFNWQLSFRWF-----SSDRKRQTAGNSSKDSTDPIATPGMAGGLFA 333
            :||||.|.|....:..:|.|||:|:|||:     ..||:|       .|.|.|:.||.||||||:
 Frog   240 VISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRR-------GDRTLPVRTPTMAGGLFS 297

  Fly   334 IDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGGRVEISPCSHVGHVFRSSTPYTFPGGMSEVL 398
            |||.||.|:|:||:.|.:|||||:|:|||||||||.:||..|||||||||.:||||||||..:::
 Frog   298 IDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQII 362

  Fly   399 TDNLARAATVWMDDWQYFIMLYTSGLTLGAKDKVNVTERVALRERLQCKPFSWYLENIWPEHFFP 463
            ..|..|.|.||||:::.|..:.:.|:|  ..|..:::.||.||.:||||||||||||::|:...|
 Frog   363 NKNNRRLAEVWMDEFKNFFYIISPGVT--KVDYGDISTRVGLRHKLQCKPFSWYLENVYPDSQIP 425

  Fly   464 APDRFFGKIIWLDGETECAQAYSKHMKNLPGRALSREWKRAFEEIDSKAEELMALIDLERDKCLR 528
                                   :|..:|.                       .:.::|.::||
 Frog   426 -----------------------RHYYSLG-----------------------EIRNVETNQCL- 443

  Fly   529 PLKEDVPRSSLSAVTVGDCTSHAQ-SMDMFVITPKGQIMTNDNVCLTYRQQKL-GVIKMLKNRNA 591
               :::.|.....|.:.:|  |.. ...:|..|...:|.| |::||..  .|| |.:.|||..:.
 Frog   444 ---DNMARKENEKVGIFNC--HGMGGNQVFSYTASKEIRT-DDLCLDV--SKLNGPVIMLKCHHL 500

  Fly   592 TTSNVMLAQCASDSSQLWTYDMDTQQISHRDTKLCLTLKAATNSRLQKVEKVVLSMECDFKDITQ 656
            .            .:|||.||.....:.|.::..||...|..:|::..:.      :|. ...:|
 Frog   501 R------------GNQLWEYDPVKLTLVHVNSNQCLDKAAEEDSQVPSIR------DCS-GSRSQ 546

  Fly   657 KW 658
            :|
 Frog   547 QW 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	pp-GalNAc-T	153..457	CDD:133004	183/308 (59%)
		beta-trefoil_Ricin_Pgant3-like	515..661	CDD:467338	33/146 (23%)
galnt1	XP_031759269.1	pp-GalNAc-T	119..419	CDD:133004	183/308 (59%)
		beta-trefoil_Ricin_GALNT1	426..552	CDD:467344	35/174 (20%)