Protein Alignment Pgant3 and GALNT16

DIOPT Version :9

• Sequence 1: NP_610256.1
• Gene: Pgant3 / 35627
• FlyBaseID: FBgn0027558
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001161840.1
• Gene: GALNT16 / 57452
• HGNCID: 23233
• Length: 558
• Species: Homo sapiens
• Alignment Length: 553
• Identity: 185/553 - (33%)
• Similarity: 271/553 - (49%)
• Gaps: 85/553 - (15%)

  Fly   113 FRLNSFNLLASDRIPLNRTLKDYRTPECRDKKYASGLPSTSVIIVFHNEAWSVLLRTITSVINRS 177
            :|.::||.|.||::..:|.::|.|...|....|:|.||:|||||.|||||.|.||||:.||:||:
Human    86 YRQHAFNQLESDKLSPDRPIRDTRHYSCPSVSYSSDLPATSVIITFHNEARSTLLRTVKSVLNRT 150

  Fly   178 PRHLLKEIILVDDASDRSYLKRQLESYVKVLAVP-TRIFRMKKRSGLVPARLLGAENARGDVLTF 241
            |.:|::|||||||.|.      ..|..:.:..:| .:..|..:|.||:.:|:.||:.|...||||
Human   151 PANLIQEIILVDDFSS------DPEDCLLLTRIPKVKCLRNDRREGLIRSRVRGADVAAATVLTF 209

  Fly   242 LDAHCECSRGWLEPLLSRIKESRKVVICPVIDIISDDNFSYTKTFENHWGAFNWQLSFRWFSSDR 306
            ||:|||.:..||.|:|.|:||....|:.|:||:||.|||:|.....:..|.|:|.|.|:|.....
Human   210 LDSHCEVNTEWLPPMLQRVKEDHTRVVSPIIDVISLDNFAYLAASADLRGGFDWSLHFKWEQIPL 274

  Fly   307 KRQTAGNSSKDSTDPIATPGMAGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGGRVE 371
            :::.   :..|.|.||.||.:|||:|.||:.:|..:|.||:.|.:|||||.|:|||:|.|||.:|
Human   275 EQKM---TRTDPTRPIRTPVIAGGIFVIDKSWFNHLGKYDAQMDIWGGENFELSFRVWMCGGSLE 336

  Fly   372 ISPCSHVGHVFRSSTPYTFPGGMSEVLTDNLARAATVWMDDW-QYFIMLYTSGLTLGAKDKVNVT 435
            |.|||.||||||...||.||.|.:.....|..|.|.||||:: ||:.....|.:   .|...:|.
Human   337 IVPCSRVGHVFRKRHPYNFPEGNALTYIRNTKRTAEVWMDEYKQYYYEARPSAI---GKAFGSVA 398

  Fly   436 ERVALRERLQCKPFSWYLENIWPEHFFPAPDRFFGKIIWLDGETECAQAYSKHMKNLPGRALSRE 500
            .|:..|:::.||.|.|||||::||...|..:.                        |||..
Human   399 TRIEQRKKMNCKSFRWYLENVYPELTVPVKEA------------------------LPGII---- 435

  Fly   501 WKRAFEEIDSKAEELMALIDLERDKCLRPLKEDVPRSSLSAVTVGDCTSHAQSMDMFVITPKGQI 565
             |:....::|:.:.......|....|....|...|             :.|......:|..:|:.
Human   436 -KQGVNCLESQGQNTAGDFLLGMGICRGSAKNPQP-------------AQAWLFSDHLIQQQGKC 486

  Fly   566 MTNDNVCLTYRQQKLGVIKMLKNRNATTSNVMLAQC-ASDSSQLWTYDMDTQQISHRDTKLCLTL 629
            :...:..:                ::..|.|:|..| ..:..|.|.  .....|.|..:.|||..
Human   487 LAATSTLM----------------SSPGSPVILQMCNPREGKQKWR--RKGSFIQHSVSGLCLET 533

  Fly   630 KAATNSRLQKVEKVVLSMECDFKDITQKWGFIP 662
            |.|.          :::.:|......|:|..:|
Human   534 KPAQ----------LVTSKCQADAQAQQWQLLP 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	Glyco_tranf_2_3	150..386	CDD:290369	113/236 (48%)
		pp-GalNAc-T	153..457	CDD:133004	138/305 (45%)
		Ricin_B_lectin	516..658	CDD:279046	22/142 (15%)
		RICIN	524..660	CDD:238092	22/136 (16%)
GALNT16	NP_001161840.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..54
		Catalytic subdomain A	122..227		54/110 (49%)
		pp-GalNAc-T	126..420	CDD:133004	138/305 (45%)
		Catalytic subdomain B	286..348		37/61 (61%)
		Ricin_B_lectin	441..543	CDD:395527	21/142 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820