DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant3 and galnt12

DIOPT Version :9

Sequence 1:	NP_610256.1	Gene:	Pgant3 / 35627	FlyBaseID:	FBgn0027558	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	XP_688194.1	Gene:	galnt12 / 559736	ZFINID:	ZDB-GENE-060503-704	Length:	578	Species:	Danio rerio

Alignment Length:	408	Identity:	188/408 - (46%)
Similarity:	248/408 - (60%)	Gaps:	31/408 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 HKNIVAHYIGKGDIFGNMTADDYNINLFQPINGEGADGRPVV--VPPRDRFRMQRFFRLNSFNLL 121
            |||:...:: |..::.....|         :|..|..||.|.  :...::...:...:.:..|..
Zfish    47 HKNVDEQFL-KRPVYEKPALD---------VNALGEMGRAVKLDLSGEEKREEEESIKKHQINTY 101

  Fly   122 ASDRIPLNRTLKDYRTPECRDKKY-ASGLPSTSVIIVFHNEAWSVLLRTITSVINRSPRHLLKEI 185
            .||||.|:|.|.:...|.||:.|| ...||:|||:|.|:|||||.||||:.||:..||..||.|:
Zfish   102 VSDRISLHRRLAERWNPLCRNLKYDYLSLPTTSVVIAFYNEAWSTLLRTVHSVLETSPDLLLNEV 166

  Fly   186 ILVDDASDRSYLKRQLESYVKVLAVPTRIFRMKKRSGLVPARLLGAENARGDVLTFLDAHCECSR 250
            |||||.|||.:||..||:|:..|. ..|:.|.:||.|||.||||||..|.|:||||||.||||..
Zfish   167 ILVDDYSDREHLKEPLENYIADLK-KVRLIRARKREGLVRARLLGASIATGEVLTFLDCHCECHE 230

  Fly   251 GWLEPLLSRIKESRKVVICPVIDIISDDNFSYT-KTFENHWGAFNWQLSFRWFS---SDRKRQTA 311
            |||||||.||||....|:|||||:|..:.|.|. ...|...|.|:|:|.|.|.|   .::||::|
Zfish   231 GWLEPLLQRIKEEPSAVVCPVIDVIDWNTFQYLGNPGEPQIGGFDWRLVFTWHSIPEHEQKRRSA 295

  Fly   312 GNSSKDSTDPIATPGMAGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGGRVEISPCS 376
                  :||.:.:|.|||||||:::|||..:|:||:.|.||||||:|.|||||||||.:||.|||
Zfish   296 ------ATDVVRSPTMAGGLFAVNKKYFLYLGTYDTGMEVWGGENLEFSFRIWQCGGSLEIHPCS 354

  Fly   377 HVGHVFRSSTPYTFPGGMSEVLTDNLARAATVWMDDWQYFIMLYTSGLTLGAKDKVNVTERVALR 441
            ||||||....||:....::     |..|||.|||||::......:....|.|..  :||:|..||
Zfish   355 HVGHVFPKKAPYSRNKALA-----NSVRAAEVWMDDFKEVYYHRSPHARLEAYG--DVTDRRKLR 412

  Fly   442 ERLQCKPFSWYLENIWPE 459
            .||:||.|.|:|:||:|:
Zfish   413 MRLRCKDFRWFLDNIYPD 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	Glyco_tranf_2_3	150..386	CDD:290369	136/239 (57%)
		pp-GalNAc-T	153..457	CDD:133004	160/307 (52%)
		Ricin_B_lectin	516..658	CDD:279046
		RICIN	524..660	CDD:238092
galnt12	XP_688194.1	pp-GalNAc-T	134..428	CDD:133004	160/307 (52%)
		Ricin_B_lectin	440..572	CDD:279046
		RICIN	442..574	CDD:238092
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820