DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant3 and galnt7

DIOPT Version :9

Sequence 1:	NP_610256.1	Gene:	Pgant3 / 35627	FlyBaseID:	FBgn0027558	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	NP_001018477.1	Gene:	galnt7 / 553668	ZFINID:	ZDB-GENE-050522-284	Length:	652	Species:	Danio rerio

Alignment Length:	623	Identity:	203/623 - (32%)
Similarity:	298/623 - (47%)	Gaps:	112/623 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 PHKNIVAH-YIGKGDIFGNMTADDYNINLFQPINGEGADGRPVVVPPRDRFRMQRFFRLNSFNLL 121
            ||.|:.:. .:.||.: ||....:...:..|...|||:  :|.|:.|..:..:|...:...||::
Zfish   112 PHTNMYSDPVLNKGTL-GNFEPKEPEPHGVQGGPGEGS--KPFVLGPEYKDAVQASIKEFGFNMV 173

  Fly   122 ASDRIPLNRTLKDYRTPECRDKKYASGLPSTSVIIVFHNEAWSVLLRTITSVINRSPRHLLKEII 186
            |||.|.|:||:.|.|..||:...|...|.::|||||||||.||.|:||:.|||.|:||..|.||:
Zfish   174 ASDMISLDRTVGDLRHEECKYWNYDENLLTSSVIIVFHNEGWSTLMRTVHSVIKRTPRKYLAEIV 238

  Fly   187 LVDDASDRSYLKRQLESYVKVLAVPTRIFRMKKRSGLVPARLLGAENAR-GDVLTFLDAHCECSR 250
            ::||.|::::||.:||.|:|......::||.:||.||:.||.:||..|. |.||.:||||||...
Zfish   239 MIDDFSNKAHLKERLEEYIKQWNGLVKVFRNEKREGLIQARSIGARKATLGKVLIYLDAHCEVGV 303

  Fly   251 GWLEPLLSRIKESRKVVICPVIDIISDDNFSYTKTFENHW---------GAFNWQLSFRW--FSS 304
            .|..||::.|.:.|.|...|:||.|..:::    |.|...         ||::|.|.::.  .||
Zfish   304 NWYAPLVAPISKDRTVCTVPLIDYIDGNDY----TIEPQQGGDEDGLARGAWDWSLLWKRVPLSS 364

  Fly   305 DRKRQTAGNSSKDSTDPIATPGMAGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGGR 369
            ..|.:     .|..|:|..:|.||||||||:|::|:|:|.||..:::|||||.|:|::||||||:
Zfish   365 REKAK-----RKHKTEPYRSPAMAGGLFAIEREFFFELGLYDPGLQIWGGENFEISYKIWQCGGQ 424

  Fly   370 VEISPCSHVGHVFR----SSTPYTFPGGMSEVLTDNLARAATVWMDDWQ-YFIMLYTSGLTLGAK 429
            :...|||.|||::|    ...|.....|.|..| .|..|...||.||:: ||.......|||...
Zfish   425 LLFVPCSRVGHIYRLQGWQGNPPPAHVGSSPTL-KNYVRVVEVWWDDYKDYFYASRPETLTLAYG 488

  Fly   430 DKVNVTERVALRERLQCKPFSWYLENI---WPEHFFPAPDRFFGKIIWLDGETECAQAYSKHMKN 491
            |   ::.....||..:||.|.|::|.|   .|.| :|.|.                       ||
Zfish   489 D---ISTLKKFREEHRCKSFKWFMEEIAYDIPLH-YPLPP-----------------------KN 526

  Fly   492 LPGRALSREWKRAFEEIDSKAEELMALIDLERDKCLRPLKEDVPRSSLSAVTVGDCTSHAQ-SMD 555
            :       ||..              :...|...|:    :.:..::...|.:|.|  |.. ...
Zfish   527 V-------EWGE--------------IRGYETSYCI----DSMGHTNGGNVEIGPC--HRMGGNQ 564

  Fly   556 MFVITPKGQIMTNDNVCLTYRQQKLGVIKMLKNRNATTSNVMLAQCASDSSQLWTYDMDTQQISH 620
            :|.|....|:|..|. |||              :....|.|::..|..:....|.|..|..:.:|
Zfish   565 LFRINEANQLMQYDQ-CLT--------------KGGDGSAVIITHCNLNEHTEWKYFKDLHRFTH 614

  Fly   621 RDTKLCLTLKAATNSRLQKVEKVVLSMECDFKDITQKW 658
            ..|..||       .|...:.||.:: :||....:|||
Zfish   615 VPTGKCL-------DRSDVLHKVYIA-DCDNSKSSQKW 644

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	Glyco_tranf_2_3	150..386	CDD:290369	109/251 (43%)
		pp-GalNAc-T	153..457	CDD:133004	133/323 (41%)
		Ricin_B_lectin	516..658	CDD:279046	30/142 (21%)
		RICIN	524..660	CDD:238092	31/136 (23%)
galnt7	NP_001018477.1	pp-GalNAc-T	205..513	CDD:133004	132/320 (41%)
		BcsA	205..>433	CDD:224136	105/236 (44%)
		Ricin_B_lectin	529..644	CDD:279046	31/157 (20%)
		RICIN	530..646	CDD:238092	32/158 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920