DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant3 and GALNT9

DIOPT Version :9

Sequence 1:	NP_610256.1	Gene:	Pgant3 / 35627	FlyBaseID:	FBgn0027558	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	NP_001116108.1	Gene:	GALNT9 / 50614	HGNCID:	4131	Length:	603	Species:	Homo sapiens

Alignment Length:	395	Identity:	154/395 - (38%)
Similarity:	218/395 - (55%)	Gaps:	35/395 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 IGKGDIFGNMTADDYNINLFQPINGEGADGRPVVVPPRDRFRMQRFFRLNSFNLLASDRIPLNRT 131
            :|:|.:...:..|           |:.|:|:               :....:|...||||.|:|:
Human    94 LGQGGLAATLRDD-----------GQEAEGK---------------YEEYGYNAQLSDRISLDRS 132

  Fly   132 LKDYRTPECRDKKYASGLPSTSVIIVFHNEAWSVLLRTITSVINRSPRHLLKEIILVDDASDRSY 196
            :.|||..:||...||..||..||:.:|.|||.||:||::.||:|.:|..||||:|||||.||...
Human   133 IPDYRPRKCRQMSYAQDLPQVSVVFIFVNEALSVILRSVHSVVNHTPSQLLKEVILVDDNSDNVE 197

  Fly   197 LKRQLESYV-KVLAVPTRIFRMKKRSGLVPARLLGAENARGDVLTFLDAHCECSRGWLEPLLSRI 260
            ||..|:.|| |......:|.|..:|.||:.|||.|.:.|...|:.|.|||.|.:.||.||.||||
Human   198 LKFNLDQYVNKRYPGLVKIVRNSRREGLIRARLQGWKAATAPVVGFFDAHVEFNTGWAEPALSRI 262

  Fly   261 KESRKVVICPVIDIISDDNFSYTKTFENHWGAFNWQLSFRWFSSDRKRQTAGNSSKDSTDPIATP 325
            :|.|:.::.|.||.|....|. .:.:.|....:||.|...:....:.....|    |.:.||.||
Human   263 REDRRRIVLPAIDNIKYSTFE-VQQYANAAHGYNWGLWCMYIIPPQDWLDRG----DESAPIRTP 322

  Fly   326 GMAGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGGRVEISPCSHVGHVFRSSTPYTF 390
            .|.|..|.:||:||.::|..|..|.|:||||||:..|:|||||.:|:.|||.|.|:.|:..||.
Human   323 AMIGCSFVVDREYFGDIGLLDPGMEVYGGENVELGMRVWQCGGSMEVLPCSRVAHIERTRKPYN- 386

  Fly   391 PGGMSEVLTDNLARAATVWMDDWQ-YFIMLYTSGLTLGAKDKVNVTERVALRERLQCKPFSWYLE 454
             ..:......|..|||.|||||:: :..|.:...::....|..:|:||:|||:||:|:.|.||||
Human   387 -NDIDYYAKRNALRAAEVWMDDFKSHVYMAWNIPMSNPGVDFGDVSERLALRQRLKCRSFKWYLE 450

  Fly   455 NIWPE 459
            |::||
Human   451 NVYPE 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	Glyco_tranf_2_3	150..386	CDD:290369	103/236 (44%)
		pp-GalNAc-T	153..457	CDD:133004	130/305 (43%)
		Ricin_B_lectin	516..658	CDD:279046
		RICIN	524..660	CDD:238092
GALNT9	NP_001116108.1	Catalytic subdomain A	150..261		54/110 (49%)
		pp-GalNAc-T	154..453	CDD:133004	130/305 (43%)
		Catalytic subdomain B	318..380		33/61 (54%)
		Ricin_B_lectin	464..592	CDD:279046
		RICIN	466..594	CDD:238092
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810