DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant3 and galnt11

DIOPT Version :9

Sequence 1:	NP_610256.1	Gene:	Pgant3 / 35627	FlyBaseID:	FBgn0027558	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	XP_031759178.1	Gene:	galnt11 / 448751	XenbaseID:	XB-GENE-981830	Length:	601	Species:	Xenopus tropicalis

Alignment Length:	668	Identity:	220/668 - (32%)
Similarity:	322/668 - (48%)	Gaps:	149/668 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 WLLYLFLLFFAFFMFAISINLYVASIQGGDAEMRHP--------KPPPKRRSLWP---HKNIVAH 65
            |.|.||:    :|.|:       ...||    .||.        ||.||:  ::|   ..::..|
Frog    20 WTLLLFI----YFNFS-------EESQG----FRHVPVKGLEPYKPLPKK--IYPRFSRDSMGQH 67

  Fly    66 YIGKGDIFGNMTADDYNINLFQPI----NGEGADGRPVVVPPRDRFRMQRFFRLNSFNLLASDRI 126
            ...:....||....:.|.:|...:    |.:..|.|.|            .::.::||||.|:|:
Frog    68 SDPRKGHNGNQLETEANADLSPELGMIFNEQDQDVRDV------------GYQKHAFNLLISNRL 120

  Fly   127 PLNRTLKDYRTPECRDKKYASGLPSTSVIIVFHNEAWSVLLRTITSVINRSPRHLLKEIILVDDA 191
            ..:|.:.|.|..:|..|.|...||..|::|.|:|||:|.||||:.||::|:|..||.|||||||.
Frog   121 GYHRDVPDTRDSKCAKKTYPPDLPMASIVICFYNEAFSALLRTVHSVLDRTPAQLLHEIILVDDN 185

  Fly   192 SDRSYLKRQLESYVKV-LAVPTRIFRMKKRSGLVPARLLGAENARGDVLTFLDAHCECSRGWLEP 255
            |:...||:.|:.|::. |:...::.|.|:|.||:..|::||.:|.||||.|||:|||.:..||:|
Frog   186 SELDDLKKDLDGYMQENLSKKVKLVRNKQREGLIRGRMVGASHATGDVLVFLDSHCEVNEMWLQP 250

  Fly   256 LLSRIKESRKVVICPVIDIISDDNFSYTKTFENHWGAFNWQLSFRWFSSDRKRQTAGNSSKDSTD 320
            ||:.|||:.:.|:||||||||.|...|:.:.... |.|||.|.|:|   |..........:..:.
Frog   251 LLAPIKENPRTVVCPVIDIISADTLIYSSSPVVR-GGFNWGLHFKW---DPVPLAELGGPEGFSA 311

  Fly   321 PIATPGMAGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGGRVEISPCSHVGHVFRSS 385
            |..:|.|||||||:||:||..:|.|||.|.:|||||:|:|||||.|||.:.|.|||.|||:||..
Frog   312 PFRSPTMAGGLFAMDREYFNMLGQYDSGMDIWGGENLEISFRIWMCGGSLLIVPCSRVGHIFRKR 376

  Fly   386 TPYTFPGGMSEVLTDNLARAATVWMDDW--QYFIMLYTSGLTLGAKDKVNVTERVALRERLQCKP 448
            .||..||| .:.:..|..|.|.||||::  |||.:    ...|..:|..::.||:|||.||.||.
Frog   377 RPYGSPGG-HDTMAHNSLRLAHVWMDEYKDQYFAL----RPELRNRDFGDIRERLALRRRLNCKS 436

  Fly   449 FSWYLENIWPEHFFPAPDRFFGKIIWLDGETECAQAYSKHMKNLPGRALSREWKRAFEEIDSKAE 513
            |.|||:||:||                      .|....:.|..|...:::..||      .|..
Frog   437 FKWYLDNIYPE----------------------MQVSGPNAKPQPPVFMNKGQKR------PKIL 473

  Fly   514 ELMALIDLERDKCLRPLKEDVPRSSLSAVTVGDCTSHAQSMDMFVITPKGQIMTNDNVCLTYRQQ 578
            :...||:::.::||                                           |...:..|
Frog   474 QRGRLINMQTNRCL-------------------------------------------VAQGHPSQ 495

  Fly   579 KLGVIKMLKNRNATTSNVMLAQC-ASDSSQLWTYDMDTQQISHRDTKLCLTLKAATNSRLQKVEK 642
            |.|:             |:..:| .:||.|:|:|:.:.:.|  ....|||.:....:|...::
Frog   496 KGGL-------------VVAKECDYNDSEQVWSYNEEHELI--LSNLLCLDMSETRSSDPPRL-- 543

  Fly   643 VVLSMECDFKDITQKWGF 660
                |:|.....:|:|.|
Frog   544 ----MKCHGSGGSQQWVF 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	Glyco_tranf_2_3	150..386	CDD:290369	118/236 (50%)
		pp-GalNAc-T	153..457	CDD:133004	148/306 (48%)
		Ricin_B_lectin	516..658	CDD:279046	23/142 (16%)
		RICIN	524..660	CDD:238092	22/136 (16%)
galnt11	XP_031759178.1	pp-GalNAc-T	147..445	CDD:133004	148/306 (48%)
galnt11	XP_031759178.1	Ricin_B_lectin	476..597	CDD:395527	25/146 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920