DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant3 and Pgant5

DIOPT Version :9

Sequence 1:	NP_610256.1	Gene:	Pgant3 / 35627	FlyBaseID:	FBgn0027558	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster

Alignment Length:	598	Identity:	253/598 - (42%)
Similarity:	336/598 - (56%)	Gaps:	118/598 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 NMTADDYNINLFQPINGE-----------------------------------------GADGRP 98
            |...||..||..:.::||                                         |..|:|
  Fly    71 NQLVDDNEINTEKSLDGESGGALIMGQGFASGGISMTYPSVVLKKWFLAPSVQEAKGKPGEMGKP 135

  Fly    99 VVVPPRDRFRMQRFFRLNSFNLLASDRIPLNRTLKDYRTPECRDKKYASGLPSTSVIIVFHNEAW 163
            |.:|...:..|:..|:.|.|||||||.|.|||:|.|.|...||.|.|||.||:||::||||||||
  Fly   136 VKIPADMKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYASKLPTTSIVIVFHNEAW 200

  Fly   164 SVLLRTITSVINRSPRHLLKEIILVDDASDRSYLKRQLESYVKVLAVPTRIFRMKKRSGLVPARL 228
            :.||||:.||||||||.||||||||||||:|.:|.:|||.||..|.|.|.:.|.:|||||:.|||
  Fly   201 TTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARL 265

  Fly   229 LGAENARGDVLTFLDAHCECSRGWLEPLLSRIKESRKVVICPVIDIISDDNFSYTKTFENHWGAF 293
            ||||:..|:|:|||||||||:.|||||||:||.::|:.|:||:||:|||:.|.|....::.||.|
  Fly   266 LGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITASDSTWGGF 330

  Fly   294 NWQLSFRWFSSDRKRQTAGNSSKDSTDPIATPGMAGGLFAIDRKYFYEMGSYDSNMRVWGGENVE 358
            ||:|:|||:....:.....|:  |.|.|:.||.||||||:||:.||||:||||..|.:|||||:|
  Fly   331 NWKLNFRWYRVPSREMARRNN--DRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGGENLE 393

  Fly   359 MSFRIWQCGGRVEISPCSHVGHVFRSSTPYTFPGGMSEVLTDNLARAATVWMDDW-QYFIMLYTS 422
            ||||:|.|||.:||:|||.||||||.|||||||||.:|::..|.||...||:||| :::...|..
  Fly   394 MSFRVWMCGGVLEIAPCSRVGHVFRKSTPYTFPGGTTEIVNHNNARLVEVWLDDWKEFYYSFYPG 458

  Fly   423 GLTLGAKDKVNVTERVALRERLQCKPFSWYLENIWPEHFFPAPDRFFGKIIWLDGETECAQAYSK 487
            .....|.|   |::|.|||:||:||.|.|||||::||...|....:.|:|  .:.|||
  Fly   459 ARKASAGD---VSDRKALRDRLKCKSFRWYLENVYPESLMPLDYYYLGEI--RNAETE------- 511

  Fly   488 HMKNLPGRALSREWKRAFEEIDSKAEELMALIDLERDKCLRPLKEDVPRSSLSAVTVGDCTSHAQ 552
                                                 .||    :.:.|.....|.:..|.....
  Fly   512 -------------------------------------TCL----DTMGRKYNEKVGISYCHGLGG 535

  Fly   553 SMDMFVITPKGQIMTNDNVCLTYRQQKLGVIKMLKNRNATTSN--VMLAQCAS-DSSQLWTYDMD 614
            : .:|..|.:.||| :|::||                :|::||  |.:.:|.: ..:|.|.||.:
  Fly   536 N-QVFAYTKRQQIM-SDDLCL----------------DASSSNGPVNMVRCHNMGGNQEWVYDAE 582

  Fly   615 TQQISHRDTKLCL 627
            .:.|.|.:|..||
  Fly   583 EKWIRHTNTGQCL 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	Glyco_tranf_2_3	150..386	CDD:290369	146/235 (62%)
		pp-GalNAc-T	153..457	CDD:133004	180/304 (59%)
		Ricin_B_lectin	516..658	CDD:279046	27/115 (23%)
		RICIN	524..660	CDD:238092	27/107 (25%)
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	180/304 (59%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	32/161 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2642
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D194016at33208
OrthoFinder	1	1.000	-	-		FOG0002015
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.870