DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant3 and Galnt9

DIOPT Version :9

Sequence 1:	NP_610256.1	Gene:	Pgant3 / 35627	FlyBaseID:	FBgn0027558	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	NP_001116116.1	Gene:	Galnt9 / 304571	RGDID:	1311523	Length:	604	Species:	Rattus norvegicus

Alignment Length:	686	Identity:	211/686 - (30%)
Similarity:	302/686 - (44%)	Gaps:	137/686 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KLWLLYLFLLFFAFFMFAISINL------YVASIQGGDAEMRHPKPPPKRRSLWPHKNIVAHYIG 68
            |..|....|:|....:|::...|      .|..::|.|..||:..  .|..:|...:.|:...
  Rat     8 KTLLTVNILVFVGIILFSVYCRLQDRSEALVQVVRGADRRMRNRL--SKASALTDREAILQRL-- 68

  Fly    69 KGDIFGNMTADDYNINLFQPI---NGEGADGRPVVVP--PRDRFRMQRFFRLNSFNLLASDRIPL 128
              |....:..:..| .|.:||   .|.|..|:..|..  ..|....:..|....:|...||||.|
  Rat    69 --DHLEEVVYNQLN-GLAKPIGLVEGPGGLGQGGVAATLQDDSQETEGKFEDFGYNAQLSDRISL 130

  Fly   129 NRTLKDYRTPECRDKKYASGLPSTSVIIVFHNEAWSVLLRTITSVINRSPRHLLKEIILVDDASD 193
            :||:.|||...||...|:..||..||:.:|.|||.||:||::.||:|.:|..||||||||||.||
  Rat   131 DRTIPDYRPKRCRQITYSEDLPQISVVFIFVNEALSVILRSVHSVVNHTPSQLLKEIILVDDNSD 195

  Fly   194 RSYLKRQLESYV-KVLAVPTRIFRMKKRSGLVPARLLGAENARGDVLTFLDAHCECSRGWLEPLL 257
            ...||..|:.|| |......::.|..:|.||:.|||.|.:.|...::.|.|||.|.:.||.||.|
  Rat   196 NVELKFNLDQYVHKRYPGLVKVVRNSRREGLIRARLQGWKVATAPIVGFFDAHVEFNTGWAEPAL 260

  Fly   258 SRIKESRKVVICPVIDIISDDNFSYTKTFENHWGA-----FNWQLSFRWFSSDRKRQTAGNSSKD 317
            :||:|.|:.:|.|.|     ||..|: |||....|     :||.|...:....:.....|    |
  Rat   261 ARIQEDRRRIILPAI-----DNIKYS-TFEVQQYASAAHGYNWGLWCMYIIPPQDWLDRG----D 315

  Fly   318 STDPIATPGMAGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGGRVEISPCSHVGHVF 382
            .:.||.||.|.|..|.:||:||.::|..|..|.|:|.||:|:..|:|||||.:|:.|||.|.|:.
  Rat   316 ESAPIRTPAMIGCSFVVDREYFGDIGLLDPGMEVYGAENIELGMRVWQCGGSMEVLPCSRVAHIE 380

  Fly   383 RSSTPYTFPGGMSEVLTDNLARAATVWMDDWQ-YFIMLYTSGLTLGAKDKVNVTERVALRERLQC 446
            |:..||.  ..:......|..|||.|||||:: :..|.:...:|....|..:|:||:|||::|:|
  Rat   381 RTKKPYN--NDIDYYAKRNALRAAEVWMDDFKSHVYMAWNIPMTNPGVDFGDVSERLALRQKLKC 443

  Fly   447 KPFSWYLENIWPEHFFPAPDRFFGKIIWLDGETECAQAYSKHMKNLPGRALSREWKRAFEEIDSK 511
            :.|.|||||::||.      |.:...:.. ||..                            :||
  Rat   444 RSFKWYLENVYPEM------RIYNNTLTY-GEVR----------------------------NSK 473

  Fly   512 AEELMALIDLERDKCLRPLKEDVPRSSLSAVTVGDCTSHAQSMDMFVITPKGQIMTN-------- 568
            |.          ..||....||..|:.|.     .|  |..|..:...:..|.:...
  Rat   474 AS----------GYCLDQGAEDDDRAILY-----PC--HGMSSQLVRYSADGLLQLGPLGSTAFL 521

  Fly   569 -DNVCLTYRQQKLGVIKMLKNRNATTSNVMLAQC---ASDSSQLWTYDMDTQQISHRDTKLCLTL 629
             |:.||         :...:.|..|     |.:|   |..:.:||.:......:| |||..||
  Rat   522 PDSKCL---------VDDGRGRMPT-----LKKCEDVARPTQRLWDFTQSGPIVS-RDTGRCL-- 569

  Fly   630 KAATNSRLQKVEKVVLSMECDF-------KDITQKW 658
                        :|.:|.:.:|       :...|||
  Rat   570 ------------EVEMSKDANFGLRLVVQRCSGQKW 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	Glyco_tranf_2_3	150..386	CDD:290369	103/241 (43%)
		pp-GalNAc-T	153..457	CDD:133004	130/310 (42%)
		Ricin_B_lectin	516..658	CDD:279046	30/160 (19%)
		RICIN	524..660	CDD:238092	32/154 (21%)
Galnt9	NP_001116116.1	pp-GalNAc-T	155..454	CDD:133004	130/310 (42%)
		Ricin_B_lectin	465..593	CDD:279046	35/202 (17%)
		RICIN	467..595	CDD:238092	37/201 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810