DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant3 and Galnt13

DIOPT Version :9

Sequence 1:	NP_610256.1	Gene:	Pgant3 / 35627	FlyBaseID:	FBgn0027558	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	XP_036018146.1	Gene:	Galnt13 / 271786	MGIID:	2139447	Length:	613	Species:	Mus musculus

Alignment Length:	698	Identity:	269/698 - (38%)
Similarity:	359/698 - (51%)	Gaps:	173/698 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LWLLY-LFLLFFAFFMFAISINLYVASIQGGDAEMRHPKPPPKRRSLWPHKNIVAHYIGKGDIFG 74
            :|:|. :|||            ||.:.....|.:        |.|||.|....|        |..
Mouse    16 MWVLVDVFLL------------LYFSECNKCDDK--------KERSLLPALRAV--------ISR 52

  Fly    75 NMTADDYNINLFQPINGEGADGRPVVVPPRDRFRMQRFFRLNSFNLLASDRIPLNRTLKDYRTP- 138
            |.             .|.|..|:.|::|..|:.:|:..|::|.|||:|||.|.|||:|.|.|..
Mouse    53 NQ-------------EGPGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEG 104

  Fly   139 -----------------------------------------ECRDKKYASGLPSTSVIIVFHNEA 162
                                                     .|:.|.|...||:|||:|||||||
Mouse   105 QYCCGRCEELQTMQQERYARVYISTNFCSSILFWLKCNTELRCKTKVYPDELPNTSVVIVFHNEA 169

  Fly   163 WSVLLRTITSVINRSPRHLLKEIILVDDASDRSYLKRQLESYVKVLAVPTRIFRMKKRSGLVPAR 227
            ||.||||:.|||||||.:||.|:|||||||:|.:||..||:|||.|.||.:|.||::||||:.||
Mouse   170 WSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKTLEVPVKIIRMEERSGLIRAR 234

  Fly   228 LLGAENARGDVLTFLDAHCECSRGWLEPLLSRIKESRKVVICPVIDIISDDNFSYTKTFENHWGA 292
            |.||..::|.|:|||||||||:.|||||||:||||.||.|:||:||:||||.|.|....:..:|.
Mouse   235 LRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDMTYGG 299

  Fly   293 FNWQLSFRWF-----SSDRKRQTAGNSSKDSTDPIATPGMAGGLFAIDRKYFYEMGSYDSNMRVW 352
            |||:|:|||:     ..||::       .|.|.|:.||.||||||:|||.||.|:|:||:.|.:|
Mouse   300 FNWKLNFRWYPVPQREMDRRK-------GDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIW 357

  Fly   353 GGENVEMSFRIWQCGGRVEISPCSHVGHVFRSSTPYTFPGGMSEVLTDNLARAATVWMDDWQYFI 417
            ||||:|||||||||||.:||..|||||||||.:||||||||...|:..|..|.|.||||:::.|.
Mouse   358 GGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFF 422

  Fly   418 MLYTSGLTLGAKDKVNVTERVALRERLQCKPFSWYLENIWPEHFFPAPDRFFGKIIWLDGETECA 482
            .:.:.|:.  ..|..:|:.|..|||.|:|||||||||||:|:.  ..|.|::
Mouse   423 YIISPGVV--KVDYGDVSVRKTLRENLKCKPFSWYLENIYPDS--QIPRRYY------------- 470

  Fly   483 QAYSKHMKNLPGRALSREWKRAFEEIDSKAEELMALIDLERDKCLRPLKEDVPRSSLSAVTVGDC 547
                                           .|..:.::|.::||    :::.|.....|.:.:|
Mouse   471 -------------------------------SLGEIRNVETNQCL----DNMGRKENEKVGIFNC 500

  Fly   548 TSHAQ-SMDMFVITPKGQIMTNDNVCLTYRQQKLGVIKMLKNRNATTSNVMLAQCASDSSQLWTY 611
              |.. ...:|..|...:|.| |::||...:.. |.:.|||..:..            .:|||.|
Mouse   501 --HGMGGNQVFSYTADKEIRT-DDLCLDVSRLS-GPVIMLKCHHMR------------GNQLWEY 549

  Fly   612 DMDTQQISHRDTKLCLTL-KAATNSRLQKVEKVVLSMECDFKDITQKW 658
            |.:|..:.|..|:.||:: |....|:       .||||.......|||
Mouse   550 DAETHTLVHIITQSCLSMGKGEDGSQ-------DLSMETCNDSTFQKW 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	Glyco_tranf_2_3	150..386	CDD:290369	150/240 (63%)
		pp-GalNAc-T	153..457	CDD:133004	183/308 (59%)
		Ricin_B_lectin	516..658	CDD:279046	35/143 (24%)
		RICIN	524..660	CDD:238092	36/137 (26%)
Galnt13	XP_036018146.1	pp-GalNAc-T	160..460	CDD:133004	183/308 (59%)
Galnt13	XP_036018146.1	Ricin_B_lectin	473..590	CDD:395527	35/143 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D194016at33208
OrthoFinder	1	1.000	-	-		FOG0002015
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920