DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant3 and Pgant9

DIOPT Version :9

Sequence 1:	NP_610256.1	Gene:	Pgant3 / 35627	FlyBaseID:	FBgn0027558	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	NP_001097342.1	Gene:	Pgant9 / 246627	FlyBaseID:	FBgn0050463	Length:	650	Species:	Drosophila melanogaster

Alignment Length:	680	Identity:	235/680 - (34%)
Similarity:	326/680 - (47%)	Gaps:	165/680 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 FAISINLYVASIQGGDAEMRHPK---PP---------------------PKRRSLWPHKNIVAHY 66
            |.|:.|:    |.||..:..|.:   ||                     ||::.....|.::.
  Fly    79 FGINGNV----IGGGGQKQAHDEADIPPTVGKHKADLQAERMRKKAAEQPKKKPQEDSKKVID-- 137

  Fly    67 IGKGDIFGNMTADDYNINLFQPINGE---GADGRPVVVPPRDRFRMQRF----FRLNSFNLLASD 124
                                .|.|.|   |..|:||.:|......|::.    :..|:||...||
  Fly   138 --------------------PPANFEENPGELGKPVRLPKEMSDEMKKAVDDGWTKNAFNQYVSD 182

  Fly   125 RIPLNRTLKDYRTPECRDK-KYASGLPSTSVIIVFHNEAWSVLLRTITSVINRSPRHLLKEIILV 188
            .|.::|||.|.|...|:|: :|.:.||.|.|||.||||||:|||||:.||::|||.||:.:||||
  Fly   183 LISVHRTLPDPRDAWCKDEARYLTNLPKTDVIICFHNEAWTVLLRTVHSVLDRSPEHLIGKIILV 247

  Fly   189 DDASDRSYLKRQLESYVKVLAVP-TRIFRMKKRSGLVPARLLGAENARGDVLTFLDAHCECSRGW 252
            ||.||..:||||||.|  ..|.| .:|.|.:||.||:.||:|||.:|:..|||:||:||||:.||
  Fly   248 DDYSDMPHLKRQLEDY--FAAYPKVQIIRGQKREGLIRARILGANHAKSPVLTYLDSHCECTEGW 310

  Fly   253 LEPLLSRIKESRKVVICPVIDIISDDNFSYTKTFENHW--------GAFNWQLSFRWFSSDRKRQ 309
            |||||.||..:...|:|||||:|||:      |.|.|:        |.|:|.|.|.|.....:.:
  Fly   311 LEPLLDRIARNSTTVVCPVIDVISDE------TLEYHYRDSGGVNVGGFDWNLQFSWHPVPERER 369

  Fly   310 TAGNSSKDSTDPIATPGMAGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGGRVEISP 374
            ...||   :.:|:.:|.||||||:|||::|..:|:|||...:|||||:|:||:.|.|||.:||.|
  Fly   370 KRHNS---TAEPVYSPTMAGGLFSIDREFFDRLGTYDSGFDIWGGENLELSFKTWMCGGTLEIVP 431

  Fly   375 CSHVGHVFRSSTPYTFPGGMSEVLTDNLARAATVWMDDW-QYFIMLYTSGLTLGAKDKVNVTERV 438
            ||||||:||..:||.:..|:: ||..|..|.|.||||:: ||:  .:..|...|  |..:|::|.
  Fly   432 CSHVGHIFRKRSPYKWRSGVN-VLKKNSVRLAEVWMDEYSQYY--YHRIGNDKG--DWGDVSDRR 491

  Fly   439 ALRERLQCKPFSWYLENIWPEHFFPAPDRFFGKI--IWLDGETEC--AQAYSKHMKNLPGRALSR 499
            .||..|:||.|.|||:||:||.|.|......|:|  :...|.| |  |.|..||.|.
  Fly   492 KLRNDLKCKSFKWYLDNIYPELFIPGDSVAHGEIRNLGYGGRT-CLDAPAGKKHQKK-------- 547

  Fly   500 EWKRAFEEIDSKAEELMALIDLERDKCLRPLKEDVPRSSLSAVTVGDCTSHAQSMDMFVITPKGQ 564
                                                       .||....|.|..:.:.:..|..
  Fly   548 -------------------------------------------AVGTYPCHRQGGNQYWMLSKAG 569

  Fly   565 IMTNDNVCLTYRQQKLGVIKMLKNRNATTSNVMLAQC-ASDSSQLWTYDMDTQQISHRDTKLCLT 628
            .:..|:.||.|                ...:|.|..| ....:|.|||..:|:|:.|..:..||.
  Fly   570 EIRRDDSCLDY----------------AGKDVTLFGCHGGKGNQFWTYRENTKQLHHGTSGKCLA 618

  Fly   629 LKAATNSRLQKVEKVVLSMECDFKDITQKW 658
            :..:.:..|.:        ||......|:|
  Fly   619 ISESKDKLLME--------ECSASLSRQQW 640

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	Glyco_tranf_2_3	150..386	CDD:290369	129/244 (53%)
		pp-GalNAc-T	153..457	CDD:133004	156/313 (50%)
		Ricin_B_lectin	516..658	CDD:279046	25/142 (18%)
		RICIN	524..660	CDD:238092	26/136 (19%)
Pgant9	NP_001097342.1	WcaA	207..>478	CDD:223539	144/284 (51%)
		pp-GalNAc-T	213..510	CDD:133004	156/312 (50%)
		Ricin_B_lectin	521..640	CDD:279046	35/194 (18%)
		RICIN	523..642	CDD:238092	36/194 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D60373at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920