DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant3 and Galnt12

DIOPT Version :9

Sequence 1:	NP_610256.1	Gene:	Pgant3 / 35627	FlyBaseID:	FBgn0027558	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	NP_766281.1	Gene:	Galnt12 / 230145	MGIID:	2444664	Length:	576	Species:	Mus musculus

Alignment Length:	392	Identity:	187/392 - (47%)
Similarity:	241/392 - (61%)	Gaps:	20/392 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 PINGEGADGRPVVVPPR-DRFRMQ-RFFRLNSFNLLASDRIPLNRTLKDYRTPECRDKKY-ASGL 149
            |.:..||.|..|.:..: :..|:| ...:.:..|:..||||.|:|.|.:...|.||:.|| ...|
Mouse    66 PADALGAHGEAVRLQLQGEELRLQEESVKQHQINIYLSDRISLHRRLPERWNPLCREVKYDYDNL 130

  Fly   150 PSTSVIIVFHNEAWSVLLRTITSVINRSPRHLLKEIILVDDASDRSYLKRQLESYVKVLAVPTRI 214
            |.|||:|.|:|||||.||||:.||:..||..||:|:|||||.|||.:||.:|.:.:..|. ..|:
Mouse   131 PKTSVVIAFYNEAWSTLLRTVYSVLETSPDILLEEVILVDDYSDREHLKERLANELSQLP-KVRL 194

  Fly   215 FRMKKRSGLVPARLLGAENARGDVLTFLDAHCECSRGWLEPLLSRIKESRKVVICPVIDIISDDN 279
            .|..:|.|||.||||||..|||:||||||.||||..|||||||.||.|....|:|||||:|..:.
Mouse   195 IRASRREGLVRARLLGASAARGEVLTFLDCHCECHEGWLEPLLQRIHEKESAVVCPVIDVIDWNT 259

  Fly   280 FSYT-KTFENHWGAFNWQLSFRW-FSSDRKRQTAGNSSKDSTDPIATPGMAGGLFAIDRKYFYEM 342
            |.|. .:.|...|.|:|:|.|.| ....|:||    |.:...|.|.:|.|||||||:.::||..:
Mouse   260 FEYLGNSGEPQIGGFDWRLVFTWHVVPQRERQ----SMRSPIDVIRSPTMAGGLFAVSKRYFDYL 320

  Fly   343 GSYDSNMRVWGGENVEMSFRIWQCGGRVEISPCSHVGHVFRSSTPYTFPGGMSEVLTDNLARAAT 407
            ||||:.|.||||||:|.|||||||||.:|..|||||||||....||:    .|:.|. |..|||.
Mouse   321 GSYDTGMEVWGGENLEFSFRIWQCGGTLETHPCSHVGHVFPKQAPYS----RSKALA-NSVRAAE 380

  Fly   408 VWMDDWQYFIMLYTSGLTLGAKDKVNVTERVALRERLQCKPFSWYLENIWPEHFFPAPDR--FFG 470
            ||||:::.  :.|........:...:||||..||.:||||.|.|:|:.::||...| .||  |||
Mouse   381 VWMDEFKE--LYYHRNPQARLEPFGDVTERKKLRAKLQCKDFKWFLDTVYPELHVP-EDRPGFFG 442

  Fly   471 KI 472
            .:
Mouse   443 ML 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	Glyco_tranf_2_3	150..386	CDD:290369	132/237 (56%)
		pp-GalNAc-T	153..457	CDD:133004	156/305 (51%)
		Ricin_B_lectin	516..658	CDD:279046
		RICIN	524..660	CDD:238092
Galnt12	NP_766281.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	38..58
		WcaA	129..424	CDD:223539	158/306 (52%)
		Catalytic subdomain A	130..239		67/109 (61%)
		pp-GalNAc-T	134..428	CDD:133004	156/305 (51%)
		Catalytic subdomain B	299..361		41/61 (67%)
		Ricin_B_lectin	440..569	CDD:279046	3/5 (60%)
		RICIN	442..571	CDD:238092	1/3 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820