Protein Alignment Pgant3 and gly-10

DIOPT Version :10

• Sequence 1: NP_610256.1
• Gene: Pgant3 / 35627
• FlyBaseID: FBgn0027558
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001041036.2
• Gene: gly-10 / 178343
• WormBaseID: WBGene00001635
• Length: 703
• Species: Caenorhabditis elegans
• Alignment Length: 692
• Identity: 212/692 - (30%)
• Similarity: 323/692 - (46%)
• Gaps: 122/692 - (17%)

  Fly     1 MGL-RFQQLKKLWLL-YLFLLFFAFFMFAISINLYVAS-------------IQGGDAEMRHPKPP 50
            ||| |:...:..|:: |..||.|.:.:::     |||:             .||...:..:|.||
 Worm    82 MGLSRYLSRRHHWVIQYCGLLLFLYLIYS-----YVATSNDGPNLHEDIPVFQGQGKDRANPNPP 141

  Fly    51 PK--RRSLWPHKNIVAHYIGKGDIFGNMTADDYNINLFQPINGEGADGRPVVVPPRDRFRMQ--R 111
            ..  ..:|.|.:....|...|.:       |:......:...|.|..|:||.:|.......:  .
 Worm   142 AALGDEALDPFEKYRGHEKIKWE-------DEAAYEKEKRREGPGEWGKPVKLPEDKEVEKEALS 199

  Fly   112 FFRLNSFNLLASDRIPLNRTLKDYRTPECRDKKYASGLPSTSVIIVFHNEAWSVLLRTITSVINR 176
            .::.|.:|...||.|.|||::||.|..||::..|::.||:.|||..||.|..|.|||::.|||||
 Worm   200 LYKANGYNAYISDMISLNRSIKDIRHKECKNMMYSAKLPTVSVIFPFHEEHNSTLLRSVYSVINR 264

  Fly   177 SPRHLLKEIILVDDASDRSYLKRQLESYVKVLAVP--TRIFRMKKRSGLVPARLLGAENARGDVL 239
            ||..||||||||||.|::..|::.||.::|...:.  .::.|.|||.||:..|.|||::|.|::|
 Worm   265 SPPELLKEIILVDDFSEKPALRQPLEDFLKKNKIDHIVKVLRTKKREGLIRGRQLGAQDATGEIL 329

  Fly   240 TFLDAHCECSRGWLEPLLSRIKESRKVVICPVIDIISDDNFSYTKTFENHWGAFNWQLSFRWFSS 304
            .|||||.|.:..||.|||..|.|..:.|:||.:|:|..:.:......|...|:|:|..::
 Worm   330 IFLDAHSEANYNWLPPLLDPIAEDYRTVVCPFVDVIDCETYEVRPQDEGARGSFDWAFNY----- 389

  Fly   305 DRKRQTAGNSSKDS-TDPIATPGMAGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGG 368
              ||.......::| |.|..:|.||||.|||..|:|:|:|.||..:.:||||..|:||::|||.|
 Worm   390 --KRLPLTKKDRESPTKPFNSPVMAGGYFAISAKWFWELGGYDEGLDIWGGEQYELSFKVWQCHG 452

  Fly   369 RVEISPCSHVGHVFRSSTPYTFPGGMSEVLTDNLARAATVWMDDWQYFIMLYTSGLTLGAKDKVN 433
            |:..:|||.|.|::|.........||.:.::.|..|.|.|||||::..:..:..|  :|..|..:
 Worm   453 RMVDAPCSRVAHIYRCKYAPFKNAGMGDFVSRNYKRVAEVWMDDYKETLYKHRPG--VGNADAGD 515

  Fly   434 VTERVALRERLQCKPFSWYLENIW--PEHFFPAPDRFFGKIIWLDGETECAQAYSKHMKNLPGRA 496
            :.....:||:||||.|.|:::.|.  .:.::||
 Worm   516 LKLMKGIREKLQCKSFDWFMKEIAFDQDKYYPA-------------------------------- 548

  Fly   497 LSREWKRAFEEIDSKAEELMALIDLERDKCL-RPLKEDVPRSSLSAVTVGDCTSHAQSMDMFV-- 558
                       ::.||.....:.::..:.|: ...||...|..|...|..|.....: .|:.:
 Worm   549 -----------VEPKASAEGEIRNVGTNFCIDTQFKEQNQRFGLRKCTSDDKDGGGE-QDLRLTR 601

  Fly   559 ---ITPKGQIMTNDNVCLTYRQQKLGVIKMLKNRNATTSNVMLAQCAS-DSSQLWTYDMDTQQIS 619
               |.|||:.:..|  |.|               :...:.|:|..|.| ..:||:.|.:..:||.
 Worm   602 WHDIRPKGRKICFD--CST---------------SVDKAPVILFDCHSMKGNQLFKYRVAQKQIY 649

  Fly   620 HRDTKLCLTLKAATNSRLQKVEKVVLSM-ECDFKDITQKWGF 660
            |..:..|||  |..|.      |..|.| :||.....|||.:
 Worm   650 HPISGQCLT--ADENG------KGFLHMKKCDSSSDLQKWAW 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	pp-GalNAc-T	153..457	CDD:133004	125/306 (41%)
		beta-trefoil_Ricin_Pgant3-like	515..661	CDD:467338	38/154 (25%)
gly-10	NP_001041036.2	pp-GalNAc-T	241..539	CDD:133004	125/306 (41%)
		beta-trefoil_Ricin_GALNT10-like	555..683	CDD:467317	38/153 (25%)