Protein Alignment Pgant3 and gly-11

DIOPT Version :10

• Sequence 1: NP_610256.1
• Gene: Pgant3 / 35627
• FlyBaseID: FBgn0027558
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001022948.1
• Gene: gly-11 / 176647
• WormBaseID: WBGene00001636
• Length: 605
• Species: Caenorhabditis elegans
• Alignment Length: 650
• Identity: 198/650 - (30%)
• Similarity: 301/650 - (46%)
• Gaps: 161/650 - (24%)

  Fly     9 KKLWLLYLFLLFFAFFMFAISINLY------VASIQGGDAEMRHPK------------------- 48
            |.:.|:.||.:....:::   :::|      |.:....|.:.:|.|
 Worm     8 KTVGLICLFSILLTIYLY---VSMYPEDNERVWNSGNADIQRKHEKLNNGGQGRHDFDDDEGAEK 69

  Fly    49 -------------PP-PKRRSLWPHKN----IVAHYIGKGDIFGNMTADDYNINLFQPINGEGAD 95
                         || ||..:.:|.::    |....:||                   |||:..|
 Worm    70 DEEDAVEKQNIAAPPLPKSFTTFPDRSKEIEIDTDLLGK-------------------INGKAED 115

  Fly    96 GRPVVVPPRDRFRMQRFFRLNSFNLLASDRIPLNRTLKDYRTPECRDKKYASGLPSTSVIIVFHN 160
            ...|           ..::...||.|.||||...|.:||.|...|....|:..||:.|:::.:.|
 Worm   116 DLQV-----------EGYKKYQFNGLLSDRIGSRRKIKDSRNARCSSLTYSDSLPAASIVVCYFN 169

  Fly   161 EAWSVLLRTITSVINRS-PRHLLKEIILVDDASDRS--------YLKRQLESYVKVLAVPTRIFR 216
            |:.|||:|.:.|:.:|: |.| |.||:||||:|:.|        |.::.:..:.||     :..:
 Worm   170 ESPSVLIRMVNSIFDRTKPEH-LHEILLVDDSSEWSNATDEAIKYREKHIIQWEKV-----KFLK 228

  Fly   217 MKKRSGLVPARLLGAENARGDVLTFLDAHCECSRGWLEPLLSRIKESRKVVICPVIDIISDDNFS 281
            ..|..||:.|::.||..|.|:||.|||:|||.:..||.|||.:||::|:.|:||:||||......
 Worm   229 TDKNEGLIRAKIFGARRANGEVLVFLDSHCEVNEEWLPPLLDQIKQNRRRVVCPIIDIIDAITMK 293

  Fly   282 YTKTFENHWGAFNWQLSFRWFSSDRKRQTAGNSSKDSTDPIATPGMAGGLFAIDRKYFYEMGSYD 346
            |.:: ....|..||.::|:|   |...::......:..:|:.:|.|||||||||::||:|:||||
 Worm   294 YVES-PVCTGGVNWAMTFKW---DYPHRSYFEDPMNYVNPLKSPTMAGGLFAIDKEYFFEIGSYD 354

  Fly   347 SNMRVWGGENVEMSFRIWQCGGRVEISPCSHVGHVFRSSTPYTFPGGMSEVLTDNLARAATVWMD 411
            ..|.|||.||||:|.|||.|||.:.|.|||.|||:||...||   |..::.:..|..|.|.||:|
 Worm   355 EGMDVWGAENVEISVRIWTCGGELLIMPCSRVGHIFRRQRPY---GIKTDSMGKNSVRLARVWLD 416

  Fly   412 DW-QYFIMLYTSGLTLGAKDKVNVTERVALRERLQCKPFSWYLENIWPEHFFPAPDR-------- 467
            :: :.|.....:..|.  .|..::|.|::||..||||||.||||||:||..   ||.
 Worm   417 EYLENFFEARPNYRTF--TDYGDLTSRISLRRNLQCKPFKWYLENIYPELL---PDNTPNQLNNQ 476

  Fly   468 --FFGK--IIWLDGETECAQAYS----------------KHMKNLPGRALSREWKRAFEEIDSKA 512
              ..||  :|.:...|.|..|.:                .||:.:      ::||.      |..
 Worm   477 ILVAGKKYLIKMANGTHCLSAENSQGRIANGNRVEMRKCNHMERM------QQWKY------SST 529

  Fly   513 EELMALIDLERDKCLRPL-KEDVPRSSLSAVTVGDCTSHAQ-SMDMFVITPKGQIMTND-NVCLT 574
            .|            |||: ...:...||..::|..|  |.| :..|:.::..|::.:.. |.|.|
 Worm   530 NE------------LRPMGSSRMCLDSLRGISVILC--HNQGAHQMWQVSNAGKLYSRSVNKCAT 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	pp-GalNAc-T	153..457	CDD:133004	130/313 (42%)
		beta-trefoil_Ricin_Pgant3-like	515..661	CDD:467338	13/62 (21%)
gly-11	NP_001022948.1	pp-GalNAc-T	162..461	CDD:133004	130/313 (42%)
		beta-trefoil_Ricin_GALNT11	482..603	CDD:467318	24/124 (19%)