Protein Alignment Pgant3 and gly-3

DIOPT Version :10

• Sequence 1: NP_610256.1
• Gene: Pgant3 / 35627
• FlyBaseID: FBgn0027558
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_498722.1
• Gene: gly-3 / 176112
• WormBaseID: WBGene00001628
• Length: 612
• Species: Caenorhabditis elegans
• Alignment Length: 626
• Identity: 245/626 - (39%)
• Similarity: 338/626 - (53%)
• Gaps: 107/626 - (17%)

  Fly    46 HPKPPPKR-RSLWPHKNIVAHYIGK---GDIFGNMTADDYNINLFQPINGEGADGRPVVVPPRDR 106
            ||..|.|: :.::|.....|:.:.|   ...||            ...:|:|..|  |.||...:
 Worm    73 HPIQPEKQEKQVYPVDKETANQLRKLMETQAFG------------PGYHGQGGTG--VTVPEDKK 123

  Fly   107 FRMQRFFRLNSFNLLASDRIPLNRTLKDYRTPECR---DKKYASGLPSTSVIIVFHNEAWSVLLR 168
            ...::.|..|.||::||:.|.:||||.|||:..||   :....:|:|.||:|||||||||:.|||
 Worm   124 TIKEKRFLENQFNVVASEMISVNRTLPDYRSDACRTSGNNLKTAGMPKTSIIIVFHNEAWTTLLR 188

  Fly   169 TITSVINRSPRHLLKEIILVDDASDRSYLKRQLESYVKVLAVPTRIFRMKKRSGLVPARLLGAEN 233
            |:.|||||||||||:|||||||.|||.||.:.|:||:|:..:|..:..::.||||:.|||.|:|.
 Worm   189 TLHSVINRSPRHLLEEIILVDDKSDRDYLVKPLDSYIKMFPIPIHLVHLENRSGLIRARLTGSEM 253

  Fly   234 ARGDVLTFLDAHCECSRGWLEPLLSRIKESRKVVICPVIDIISDDNFSYTKTFENHWGAFNWQLS 298
            |:|.:|.|||||.|.:.||||||:||:.|.||.|:.|:||:||||.|.|....|..||.|||.|:
 Worm   254 AKGKILLFLDAHVEVTDGWLEPLVSRVAEDRKRVVAPIIDVISDDTFEYVTASETTWGGFNWHLN 318

  Fly   299 FRWFSSDRKRQTAGNSSKDSTDPIATPGMAGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRI 363
            |||::..::......|  |.:.||.||.:||||||||:::||::||||..|:||||||:|:|||:
 Worm   319 FRWYAVPKRELNRRGS--DRSMPIQTPTIAGGLFAIDKQFFYDIGSYDEGMQVWGGENLEISFRV 381

  Fly   364 WQCGGRVEISPCSHVGHVFRSSTPYTFPGGMSEVLTDNLARAATVWMDDWQ-YFIMLYTSGLTLG 427
            |.|||.:||.|||.||||||..||||||||.::|:..|.||.|.||||::: :|..:..:...:.
 Worm   382 WMCGGSLEIHPCSRVGHVFRKQTPYTFPGGTAKVIHHNAARTAEVWMDEYKAFFYKMVPAARNVE 446

  Fly   428 AKDKVNVTERVALRERLQCKPFSWYLENIWPEHFFPAPDRFFGKIIWLDGETE-CAQAYSKHMKN 491
            |.|   |:||..|||.||||.|.||||||:||...||..|..|.|:  :..|| |.....|....
 Worm   447 AGD---VSERKKLRETLQCKSFKWYLENIYPEAPLPADFRSLGAIV--NRFTEKCVDTNGKKDGQ 506

  Fly   492 LPGRALSREWKRAFEEIDSKAEELMALIDLERDKCLRPLKEDVPRSSLSAVTVGDCTSHAQSMDM 556
            .||                                                 :..|.. |.....
 Worm   507 APG-------------------------------------------------IQACHG-AGGNQA 521

  Fly   557 FVITPKGQIMTNDNVCLTY-RQQKLGVIKMLKNRNATTSNVMLAQCASDS---SQLWTYDMDTQQ 617
            :.:|.||:| .:|::||:. ...::|            |.:.|.:|:...   ..::.:|.....
 Worm   522 WSLTGKGEI-RSDDLCLSSGHVYQIG------------SELKLERCSVSKINVKHVFVFDDQAGT 573

  Fly   618 ISHRDTKLCLTLKAATNSRLQKVEKVVLSMECDFKDITQKW 658
            :.|:.|..|:|         ...::|.|. ||......|.|
 Worm   574 LLHKKTGKCVT---------GADQRVTLD-ECGLGRKDQMW 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	pp-GalNAc-T	153..457	CDD:133004	173/304 (57%)
		beta-trefoil_Ricin_Pgant3-like	515..661	CDD:467338	24/148 (16%)
gly-3	NP_498722.1	pp-GalNAc-T	173..473	CDD:133004	173/304 (57%)
		beta-trefoil_Ricin_GALNT1-like	481..608	CDD:467311	33/199 (17%)