Protein Alignment Pgant3 and galnt3

DIOPT Version :10

• Sequence 1: NP_610256.1
• Gene: Pgant3 / 35627
• FlyBaseID: FBgn0027558
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: XP_002936794.2
• Gene: galnt3 / 100488466
• XenbaseID: XB-GENE-954414
• Length: 625
• Species: Xenopus tropicalis
• Alignment Length: 692
• Identity: 249/692 - (35%)
• Similarity: 342/692 - (49%)
• Gaps: 160/692 - (23%)

  Fly     1 MGLRFQQLKKLWLLYLFLLFFAFFMFAISINLYVASIQGGDAEMRHPKPPPKRRSLWPHKNIVAH 65
            :|.||..    |.|....|.|..|:|.|.                      |....|....:.||
 Frog     9 LGRRFIH----WKLGFITLIFMGFLFMIQ----------------------KEVIDWEKDELGAH 47

  Fly    66 YIGK-----------GDIFGNMTADDYNINLFQPINGE--------------------------- 92
            . ||           .:|..:|.....|..:.|..||:
 Frog    48 R-GKKKMLDMMMEAVNNIKDSMPKMQINAPVRQTDNGDNVRPCLPGYYTAAELKPFLERPPQDPH 111

  Fly    93 --GADGRPV---VVPPRDRFRMQRFFRLNSFNLLASDRIPLNRTL-KDYRTPECRDKKY--ASGL 149
              ||.|:|.   .:.|.::...:|..:.:.||..|:|||.|:|.| .|.|.|||.::|:  ...|
 Frog   112 APGAAGKPFKEEKLTPEEQEEKERGEKKHCFNAFATDRISLHRDLGPDTRPPECIEQKFKRCPPL 176

  Fly   150 PSTSVIIVFHNEAWSVLLRTITSVINRSPRHLLKEIILVDDASDRSYLKRQLESYVKVLAVPTRI 214
            |:||:||||||||||.||||:.||::.||..||||||||||||...|||.:|:.|||.|.: .::
 Frog   177 PTTSIIIVFHNEAWSTLLRTVYSVMHTSPAILLKEIILVDDASVDEYLKDELDEYVKQLQI-VKV 240

  Fly   215 FRMKKRSGLVPARLLGAENARGDVLTFLDAHCECSRGWLEPLLSRIKESRKVVICPVIDIISDDN 279
            .|.|:|.||:.||||||..|.||.||||||||||..|||||||:||.|:...|:.|.|..|..:.
 Frog   241 VRQKERKGLITARLLGASVATGDTLTFLDAHCECYYGWLEPLLARIAENYTSVVSPDITGIDLNT 305

  Fly   280 FSYTKTF---ENH-WGAFNWQLSFRWF---SSDRKRQTAGNSSKDSTDPIATPGMAGGLFAIDRK 337
            |.::...   .|| .|.|:|.|||.|.   ||::.|:      ||.|.||.||..|||||:|.:.
 Frog   306 FQFSNPSPYGNNHNRGNFDWTLSFGWESLPSSEKTRR------KDETYPIKTPTFAGGLFSISKA 364

  Fly   338 YFYEMGSYDSNMRVWGGENVEMSFRIWQCGGRVEISPCSHVGHVFRSSTPYTFPGGMSEVLTDNL 402
            ||..:||||..|.:|||||:|||||:|||||::||.|||.|||||||.:|:|||.| ::|:..|.
 Frog   365 YFEHIGSYDEQMEIWGGENIEMSFRVWQCGGQLEILPCSVVGHVFRSKSPHTFPKG-TQVIVRNQ 428

  Fly   403 ARAATVWMDDWQ--YFIMLYTSGLTLGAKDKVNVTERVALRERLQCKPFSWYLENIWPEHFFPAP 465
            .|.|.|||||.:  ::.....:...:.:|:..::::|:.||.|||||.|:|||.||:||.:  .|
 Frog   429 VRLAEVWMDDLKEIFYRRNREAANIVKSKEYGDLSKRLDLRHRLQCKNFTWYLNNIYPEMY--VP 491

  Fly   466 DRF---------FGKIIWLD--GETECAQ---AYSKHMKNLPGRALSREWKRAFEEIDSKAEELM 516
            :|.         .|:.:.||  ||....:   .||.|  .|.|        ..:.|..||.|
 Frog   492 ERHPLIHGDLKNVGRDLCLDVGGENHGDKPLIMYSCH--GLGG--------NQYFEYTSKHE--- 543

  Fly   517 ALIDLERDKCLRPLKEDVPRSSLSAVTVGDCTSHAQSMDMFVITP---------KGQIMTND--N 570
            ...:::::.||||        |.|::.:..|....:.     ..|         :.|::.|.  |
 Frog   544 IRHNIQKELCLRP--------SHSSLVIKPCNYRGRD-----TAPLPEERWELQREQLLFNPSYN 595

  Fly   571 VCLTYRQQKLGVIKMLKNRNATTSNVMLAQC-ASDSSQLWTY 611
            :|:                ::..:|..|.|| .:|..|.|.:
 Frog   596 LCV----------------SSEGANPTLVQCNPADPFQQWIF 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	pp-GalNAc-T	153..457	CDD:133004	165/312 (53%)
		beta-trefoil_Ricin_Pgant3-like	515..661	CDD:467338	19/109 (17%)
galnt3	XP_002936794.2	pp-GalNAc-T	180..485	CDD:133004	165/312 (53%)
		beta-trefoil_Ricin-like	495..622	CDD:483949	33/169 (20%)