DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant3 and Galnt6

DIOPT Version :9

Sequence 1:	NP_610256.1	Gene:	Pgant3 / 35627	FlyBaseID:	FBgn0027558	Length:	667	Species:	Drosophila melanogaster
Sequence 2:	NP_001165534.1	Gene:	Galnt6 / 100361647	RGDID:	2319726	Length:	622	Species:	Rattus norvegicus

Alignment Length:	572	Identity:	227/572 - (39%)
Similarity:	304/572 - (53%)	Gaps:	105/572 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 QPINGEGADGRPVVVPPRDRFRMQRF-----------FRLNSFNLLASDRIPLNRTL-KDYRTPE 139
            |..|..||||:        .|:.:.:           ::.:.||..|||||.|.|:| .|.|.||
  Rat   108 QDPNSPGADGK--------AFQKKEWTLLETQEKDEGYKKHCFNAFASDRISLQRSLGPDTRPPE 164

  Fly   140 CRDKKY--ASGLPSTSVIIVFHNEAWSVLLRTITSVINRSPRHLLKEIILVDDASDRSYLKRQLE 202
            |.|:|:  ...||:|||:|||||||||.||||:.||::.||..||||||||||||...:||.:||
  Rat   165 CVDQKFRRCPPLPTTSVVIVFHNEAWSTLLRTVYSVLHTSPAILLKEIILVDDASTDEHLKEKLE 229

  Fly   203 SYVKVLAVPTRIFRMKKRSGLVPARLLGAENARGDVLTFLDAHCECSRGWLEPLLSRIKESRKVV 267
            .||:.|.: .|:.|.::|.||:.||||||..|:.:|||||||||||..|||||||:||.|.:..|
  Rat   230 RYVQQLQI-VRVVRQQERKGLITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDKTAV 293

  Fly   268 ICPVIDIISDDNFSYTKTFE----NHWGAFNWQLSFRW-FSSDRKRQTAGNSSKDSTDPIATPGM 327
            :.|.|..|..:.|.::|...    :..|.|:|.|:|.| ...:.::|    ..||.|.||.:|..
  Rat   294 VSPDIVTIDLNTFQFSKPMRRGKAHSRGNFDWSLTFGWEMLPEHEKQ----RRKDETYPIKSPTF 354

  Fly   328 AGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGGRVEISPCSHVGHVFRSSTPYTFPG 392
            |||||:|.:.||..:|:||:.|.:|||||||||||:|||||::||.|||.||||||:.:|:|||.
  Rat   355 AGGLFSISKAYFEHIGTYDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPK 419

  Fly   393 GMSEVLTDNLARAATVWMDDWQYFIMLYTSGLTLGAKDKVN----VTERVALRERLQCKPFSWYL 453
            |.| |:..|..|.|.|||||  |..:.|...|......|.|    |:||:.|||:|.|..|||||
  Rat   420 GTS-VIARNQVRLAEVWMDD--YKKIFYRRNLQAAKMAKENNFGDVSERLRLREQLHCHNFSWYL 481

  Fly   454 ENIWPEHFFPAPDRFFGKIIWLDGETECAQA------------YSKHMKNLPGRALSREWKRAFE 506
            .|::||.|.|..:..|...|...|.::|...            |..|  ||.|       .:.||
  Rat   482 HNVYPEMFVPDLNPTFSGAIKNLGTSQCLDVGENNRGGKPLIMYVCH--NLGG-------NQYFE 537

  Fly   507 EIDSKAEELMALIDLE----RDKCLRPLKEDVPRSSLSAVTVGDC-----TSHAQSMDMFVITPK 562
            ....:        ||.    :..||        .:|.|.:.:.:|     .|.....:.:.:| :
  Rat   538 YTSQR--------DLRHNIGKQLCL--------HASGSTLGLRNCQFIGKNSEVPKDEEWELT-Q 585

  Fly   563 GQIMTN--DNVCLTYRQQKLGVIKMLKNRNATTSNVMLAQC-ASDSSQLWTY 611
            .|::.|  ...|||.:.:|                ..:|.| .||..|||.:
  Rat   586 DQLIRNLGSGTCLTSKDKK----------------PAMAPCNPSDPYQLWLF 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	Glyco_tranf_2_3	150..386	CDD:290369	131/240 (55%)
		pp-GalNAc-T	153..457	CDD:133004	163/312 (52%)
		Ricin_B_lectin	516..658	CDD:279046	22/108 (20%)
		RICIN	524..660	CDD:238092	20/96 (21%)
Galnt6	NP_001165534.1	pp-GalNAc-T	180..485	CDD:133004	163/312 (52%)
Galnt6	NP_001165534.1	Ricin_B_lectin	497..619	CDD:395527	31/163 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D606683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11675
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020