Protein Alignment Pgant3 and Galnt6

DIOPT Version :10

• Sequence 1: NP_610256.1
• Gene: Pgant3 / 35627
• FlyBaseID: FBgn0027558
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_001165534.1
• Gene: Galnt6 / 100361647
• RGDID: 2319726
• Length: 622
• Species: Rattus norvegicus
• Alignment Length: 572
• Identity: 227/572 - (39%)
• Similarity: 304/572 - (53%)
• Gaps: 105/572 - (18%)

  Fly    87 QPINGEGADGRPVVVPPRDRFRMQRF-----------FRLNSFNLLASDRIPLNRTL-KDYRTPE 139
            |..|..||||:        .|:.:.:           ::.:.||..|||||.|.|:| .|.|.||
  Rat   108 QDPNSPGADGK--------AFQKKEWTLLETQEKDEGYKKHCFNAFASDRISLQRSLGPDTRPPE 164

  Fly   140 CRDKKY--ASGLPSTSVIIVFHNEAWSVLLRTITSVINRSPRHLLKEIILVDDASDRSYLKRQLE 202
            |.|:|:  ...||:|||:|||||||||.||||:.||::.||..||||||||||||...:||.:||
  Rat   165 CVDQKFRRCPPLPTTSVVIVFHNEAWSTLLRTVYSVLHTSPAILLKEIILVDDASTDEHLKEKLE 229

  Fly   203 SYVKVLAVPTRIFRMKKRSGLVPARLLGAENARGDVLTFLDAHCECSRGWLEPLLSRIKESRKVV 267
            .||:.|.: .|:.|.::|.||:.||||||..|:.:|||||||||||..|||||||:||.|.:..|
  Rat   230 RYVQQLQI-VRVVRQQERKGLITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDKTAV 293

  Fly   268 ICPVIDIISDDNFSYTKTFE----NHWGAFNWQLSFRW-FSSDRKRQTAGNSSKDSTDPIATPGM 327
            :.|.|..|..:.|.::|...    :..|.|:|.|:|.| ...:.::|    ..||.|.||.:|..
  Rat   294 VSPDIVTIDLNTFQFSKPMRRGKAHSRGNFDWSLTFGWEMLPEHEKQ----RRKDETYPIKSPTF 354

  Fly   328 AGGLFAIDRKYFYEMGSYDSNMRVWGGENVEMSFRIWQCGGRVEISPCSHVGHVFRSSTPYTFPG 392
            |||||:|.:.||..:|:||:.|.:|||||||||||:|||||::||.|||.||||||:.:|:|||.
  Rat   355 AGGLFSISKAYFEHIGTYDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPK 419

  Fly   393 GMSEVLTDNLARAATVWMDDWQYFIMLYTSGLTLGAKDKVN----VTERVALRERLQCKPFSWYL 453
            |.| |:..|..|.|.|||||  |..:.|...|......|.|    |:||:.|||:|.|..|||||
  Rat   420 GTS-VIARNQVRLAEVWMDD--YKKIFYRRNLQAAKMAKENNFGDVSERLRLREQLHCHNFSWYL 481

  Fly   454 ENIWPEHFFPAPDRFFGKIIWLDGETECAQA------------YSKHMKNLPGRALSREWKRAFE 506
            .|::||.|.|..:..|...|...|.::|...            |..|  ||.|       .:.||
  Rat   482 HNVYPEMFVPDLNPTFSGAIKNLGTSQCLDVGENNRGGKPLIMYVCH--NLGG-------NQYFE 537

  Fly   507 EIDSKAEELMALIDLE----RDKCLRPLKEDVPRSSLSAVTVGDC-----TSHAQSMDMFVITPK 562
            ....:        ||.    :..||        .:|.|.:.:.:|     .|.....:.:.:| :
  Rat   538 YTSQR--------DLRHNIGKQLCL--------HASGSTLGLRNCQFIGKNSEVPKDEEWELT-Q 585

  Fly   563 GQIMTN--DNVCLTYRQQKLGVIKMLKNRNATTSNVMLAQC-ASDSSQLWTY 611
            .|::.|  ...|||.:.:|                ..:|.| .||..|||.:
  Rat   586 DQLIRNLGSGTCLTSKDKK----------------PAMAPCNPSDPYQLWLF 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant3	NP_610256.1	pp-GalNAc-T	153..457	CDD:133004	163/312 (52%)
		beta-trefoil_Ricin_Pgant3-like	515..661	CDD:467338	22/109 (20%)
Galnt6	NP_001165534.1	pp-GalNAc-T	180..485	CDD:133004	163/312 (52%)
		beta-trefoil_Ricin-like	495..622	CDD:483949	33/169 (20%)