Protein Alignment Tsp42Ep and CD37

DIOPT Version :10

• Sequence 1: NP_523642.1
• Gene: Tsp42Ep / 35626
• FlyBaseID: FBgn0033137
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: XP_005259492.1
• Gene: CD37 / 951
• HGNCID: 1666
• Length: 365
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 67/302 - (22%)
• Similarity: 115/302 - (38%)
• Gaps: 104/302 - (34%)

  Fly     4 CYNTIKYTGLLSNLLYMLLG-----IGV---------MSGAGLG---LQMAEPNTPEHTYFVKSL 51
            |.:.|||...:.||.:.:||     .|:         :|..||.   ||:          :.|.|
Human     7 CLSLIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFVGLAFVPLQI----------WSKVL 61

  Fly    52 VLGGSICM-IVMFGCYGMVANLLC-VNLIFTMFIL---------IALAAEYLQLHHYHSPSLRSP 105
            .:.|...| |.:.||.|.:..|.| :.|.|.|.:|         |.::.:..||..    |||
Human    62 AISGIFTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLER----SLR-- 120

  Fly   106 GGAWQQLELAWHGLDRDPELMHQYEASQH------CCGYNGADDYKRLHLL---------VPASC 155
                ..:|........:||.....|:..:      |||::...|:.::.:|         ||.||
Human   121 ----DVVEKTIQKYGTNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSC 181

  Fly   156 YQ-AAVNDTA-------------------------------QQIYPSGCLETLNRSQRYIQHRDK 188
            |. :|.||:.                               ..||..||.:.|   |:::.:.
Human   182 YNLSATNDSTILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGL---QKWLHNN-- 241

  Fly   189 LYMWAIVGLEIFILLQTVALSVLLFRLRQRQRIARRQVPPGV 230
              :.:|||:.:.:.|  :.::|::..::.::|..||:..|.|
Human   242 --LISIVGICLGVGL--LEMTVMVLSVQLQRRALRRKCEPHV 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ep	NP_523642.1	Tetraspanin	23..213	CDD:459767	55/264 (21%)
		tetraspanin_LEL	91..183	CDD:239401	28/138 (20%)
CD37	XP_005259492.1	Tetraspanin	26..266	CDD:459767	55/268 (21%)
		CD37_CD82_like_LEL	108..243	CDD:239413	28/151 (19%)