Protein Alignment Tsp42Ep and UPK1B

DIOPT Version :10

• Sequence 1: NP_523642.1
• Gene: Tsp42Ep / 35626
• FlyBaseID: FBgn0033137
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_008883.2
• Gene: UPK1B / 7348
• HGNCID: 12578
• Length: 260
• Species: Homo sapiens
• Alignment Length: 224
• Identity: 48/224 - (21%)
• Similarity: 82/224 - (36%)
• Gaps: 80/224 - (35%)

  Fly     6 NTIK-YTGLLSNLLYMLLGIGVMSGAGLGLQMAEPNTPEHTYFVK---SL-----------VLGG 55
            :|:: :.|||      :.|..::...|:.|      |.|..:||.   ||           :.|.
Human     6 STVRCFQGLL------IFGNVIIGCCGIAL------TAECIFFVSDQHSLYPLLEATDNDDIYGA 58

  Fly    56 S-------ICM--IVMFGCYGMVANLLCVNLIFTMFILIALAAE------------------YLQ 93
            :       ||:  :.:.|..|::.:...:.|.:.:.:.|..|.|                  :|:
Human    59 AWIGIFVGICLFCLSVLGIVGIMKSSRKILLAYFILMFIVYAFEVASCITAATQQDFFTPNLFLK 123

  Fly    94 --LHHYHSPSLRSPGGAWQQ--LELAWHGLDRDPELMHQYEASQHCCGYNGADDYKRLHLLVPAS 154
              |..|.:.|..:....|:.  :...|   ||   ||.|    .:|||.||..|:::.     .|
Human   124 QMLERYQNNSPPNNDDQWKNNGVTKTW---DR---LMLQ----DNCCGVNGPSDWQKY-----TS 173

  Fly   155 CYQAAVNDTAQQIYPSGCL------ETLN 177
            .::...|| |...:|..|.      |.||
Human   174 AFRTENND-ADYPWPRQCCVMNNLKEPLN 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ep	NP_523642.1	Tetraspanin	23..213	CDD:459767	44/206 (21%)
		tetraspanin_LEL	91..183	CDD:239401	26/97 (27%)
UPK1B	NP_008883.2	Tetraspanin	14..>161	CDD:459767	32/168 (19%)
		uroplakin_I_like_LEL	118..230	CDD:239409	26/100 (26%)