Protein Alignment Tsp42Ep and tsp-16

DIOPT Version :10

• Sequence 1: NP_523642.1
• Gene: Tsp42Ep / 35626
• FlyBaseID: FBgn0033137
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_509183.2
• Gene: tsp-16 / 192066
• WormBaseID: WBGene00006642
• Length: 311
• Species: Caenorhabditis elegans
• Alignment Length: 311
• Identity: 55/311 - (17%)
• Similarity: 99/311 - (31%)
• Gaps: 118/311 - (37%)

  Fly    14 LSNLLYMLLGIGVMSGA----GLGLQMAEPNTPEHTYFVKSLVLGGSI---C--MIVMFGC---- 65
            |...|.:||.:..|.|:    |.|:|     |.....|..| |:|.::   |  ::::.|.
 Worm    17 LKKCLALLLSVLTMIGSGFIVGFGIQ-----TLREVSFTAS-VIGTNLIVYCPYLLILVGILSFV 75

  Fly    66 ------YGMVAN---LLCVNLIFTMFILIALAAEYLQLHHYHSPSLRSPGGAWQQLELAWHGLDR 121
                  :.::.|   ::..::..|:|.....|...:..:..:|....|....|.:     |.:..
 Worm    76 MTPVRFFSIILNDNKIMITHMFATIFFATICAMTAILGYDLNSHVSSSDMEHWMK-----HSIKE 135

  Fly   122 D------PELMHQYEASQH---CCGYNGADDY----------KRLHLLVPASC------------ 155
            |      |.:|.::..:..   |||.....|:          |.....:|.||
 Worm   136 DYGNPTAPHIMEEWNKAHRQFKCCGVRNLTDFVESKWYIMQKKHPRQRIPDSCCASCATMHERFC 200

  Fly   156 -----------YQAAVNDTA-----------------QQI----------------YPSGCLETL 176
                       :|...|.|.                 :::                |..||||.|
 Worm   201 VAFFKEPGNQPHQLVKNQTICLQASNGCLSADSSIANREVCQHYSSDYRLSADAYRYTGGCLEPL 265

  Fly   177 NRSQRYIQHRDKLYMWAIVGLEIFILLQTVALSVLLFRLRQRQRIARRQVP 227
            ..:..:...|..:|..:        .|..:|||.|::.|  ..:|:|..:|
 Worm   266 RTTLEFFSFRIFIYSLS--------FLAFLALSTLIWLL--NYQISREALP 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ep	NP_523642.1	Tetraspanin	23..213	CDD:459767	47/286 (16%)
		tetraspanin_LEL	91..183	CDD:239401	24/166 (14%)
tsp-16	NP_509183.2	Tetraspanin	26..174	CDD:459767	27/158 (17%)
		uroplakin_I_like_LEL	118..210	CDD:239409	15/96 (16%)