Protein Alignment Tsp42Eo and CD151

DIOPT Version :10

• Sequence 1: NP_523641.2
• Gene: Tsp42Eo / 35625
• FlyBaseID: FBgn0033136
• Length: 219
• Species: Drosophila melanogaster
• Sequence 2: NP_004348.2
• Gene: CD151 / 977
• HGNCID: 1630
• Length: 253
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 55/246 - (22%)
• Similarity: 96/246 - (39%)
• Gaps: 40/246 - (16%)

  Fly     6 VCLQWTSVVFSTLTLIVGVLAALAGVYELDKFNE-----GSAEHTEKFVQLGMAGALIL-AGLVG 64
            |||::....::....:.|:.....|::.|...::     .|..:......|.:||.::: .|::|
Human    14 VCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTGVLG 78

  Fly    65 CLGAIFGSIKVMVVNLILLLAL----IASHIWKVSHYNETKQLDATEV--YVMDLWMKELVHHG- 122
            |.........::.:..||||.:    |.:.|...::|   :||: ||:  .:.|...|.....|
Human    79 CCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYY---QQLN-TELKENLKDTMTKRYHQPGH 139

  Fly   123 -----AMQDLQQEYECCGDKGFSDYTSL---------NMKVPRSCFHT-------KDGIHALYPY 166
                 |:..||||:.|||.....|:...         ...||.||..|       :|....:|..
Human   140 EAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQRDHASNIYKV 204

  Fly   167 GEGCMAAVKRAYLQIYRYEKWVHCGLIGYEVVGIILGITLCCQLTNKTRRY 217
            ..||:..::....:..|....|..|:...:|.|:|  .|.|...:.|...|
Human   205 EGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMI--FTCCLYRSLKLEHY 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eo	NP_523641.2	Tetraspanin	8..208	CDD:459767	50/233 (21%)
		tetraspanin_LEL	110..178	CDD:239401	21/89 (24%)
CD151	NP_004348.2	Tetraspanin	16..246	CDD:459767	51/235 (22%)
		CD151_like_LEL	112..220	CDD:239408	26/111 (23%)