Protein Alignment Tsp42En and TSPAN18

DIOPT Version :10

• Sequence 1: NP_523640.1
• Gene: Tsp42En / 35624
• FlyBaseID: FBgn0033135
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: XP_005253274.1
• Gene: TSPAN18 / 90139
• HGNCID: 20660
• Length: 258
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 53/255 - (20%)
• Similarity: 86/255 - (33%)
• Gaps: 82/255 - (32%)

  Fly     2 DCRTSFLKAVLIVLNVLLSLIGVTLIALSVYELNSSTPGTFEHIAIVVQIFVGTFVVLT------ 60
            || .|.:|.::.|.|..:.|.|..|:|:.::.:...| |..|.:|....:..|.:::|.
Human    14 DC-LSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPT-GFREIVAANPLLLTGAYILLAMGGLLF 76

  Fly    61 --SFLGCFATARVSLGLVWSYVICLLILLCLQIYIIAAAH-----------------------ST 100
              .||||....|.:.        |||:...|.|.||..|.                       :.
Human    77 LLGFLGCCGAVRENK--------CLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTK 133

  Fly   101 DYVERSKKD-FLATWADQRTNVERISLLEQKYSCCGQLGAHDY---------ILMGRGIPLSCYK 155
            .|...:..| |.|||     |...|:     :.|||..|..|:         .|....:|.:|.:
Human   134 HYQGNNDTDVFSATW-----NSVMIT-----FGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCR 188

  Fly   156 DQER---------------REYSLFSGGCLQAV------QAHATDNVAIGLIIKWLLLLV 194
            .:.:               |...|...||...:      ..:....:|||::...|..::
Human   189 REPQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMI 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42En	NP_523640.1	Tetraspanin	8..>135	CDD:459767	35/158 (22%)
		tetraspanin_LEL	96..180	CDD:239401	21/137 (15%)
TSPAN18	XP_005253274.1	Tetraspanin	20..255	CDD:459767	50/248 (20%)
		uroplakin_I_like_LEL	115..228	CDD:239409	20/122 (16%)