Protein Alignment Tsp42En and Tspan15

DIOPT Version :10

• Sequence 1: NP_523640.1
• Gene: Tsp42En / 35624
• FlyBaseID: FBgn0033135
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_932113.2
• Gene: Tspan15 / 70423
• MGIID: 1917673
• Length: 294
• Species: Mus musculus
• Alignment Length: 243
• Identity: 60/243 - (24%)
• Similarity: 107/243 - (44%)
• Gaps: 45/243 - (18%)

  Fly     7 FLKAVLIVLNVLLSLIGVTLIALSVY-ELNSSTPGTFEHIAI---VVQIFVGTFVVLTSFLGCFA 67
            :||..||:.:.:..|||..::::.:| |.......|.|...:   ::.|.:|..:.:.||:|..|
Mouse    19 WLKFSLIIYSTVFWLIGGLVLSVGIYAEAERQKYKTLESAFLAPAIILILLGVVMFIVSFIGVLA 83

  Fly    68 TARVSLGLVWSYVICLLILLCLQ-----IYIIAAAHSTDYVERSKKDFLATWADQRTNVERISLL 127
            :.|.:|.|:.|::..|.|.|.::     :.:|....:.|::..:.:..:..:.|.......:..:
Mouse    84 SLRDNLCLLQSFMYILGICLVMELIGGIVALIFRNQTIDFLNDNIRRGIENYYDDLDFKNIMDFV 148

  Fly   128 EQKYSCCG--------QLGAHDYILMGR---GIPLSC--------------YK--DQER--REYS 163
            ::|:.|||        :...||....|.   |:|.:|              ||  |:||  .:..
Mouse   149 QKKFKCCGGEDYRDWSKNQYHDCSAPGPLACGVPYTCCIRNTTDVVNTMCGYKTIDKERLNAQNI 213

  Fly   164 LFSGGCLQAVQAHATDNVAI--GLIIKWLLLLVEFAALGA-ATHLGIT 208
            :...||..||.....||..|  ||::.  :||.:|  ||. .|.|.||
Mouse   214 IHVRGCTNAVLIWFMDNYTIMAGLLLG--ILLPQF--LGVLLTLLYIT 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42En	NP_523640.1	Tetraspanin	8..>135	CDD:459767	29/135 (21%)
		tetraspanin_LEL	96..180	CDD:239401	21/112 (19%)
Tspan15	NP_932113.2	Tetraspanin	20..>157	CDD:459767	30/136 (22%)
		penumbra_like_LEL	114..231	CDD:239411	23/116 (20%)