Protein Alignment Tsp42En and Tspan12

DIOPT Version :10

• Sequence 1: NP_523640.1
• Gene: Tsp42En / 35624
• FlyBaseID: FBgn0033135
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_766595.1
• Gene: Tspan12 / 269831
• MGIID: 1889818
• Length: 305
• Species: Mus musculus
• Alignment Length: 204
• Identity: 43/204 - (21%)
• Similarity: 83/204 - (40%)
• Gaps: 49/204 - (24%)

  Fly     8 LKAVLIVLNVLLSLIGVTLIALSVY---ELNSSTPGTFE----------HIAIV--VQIFVGTFV 57
            |:.:|..||:|..|:.::::|:|.:   .||:....|.|          :..:|  |.|.|..|:
Mouse    10 LRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIAVCCFL 74

  Fly    58 VLTSFLGCFATARVSLGLVWSYVICLLILLCLQIYIIAAAHSTDYVERSKKDFLATWADQRTNVE 122
            ::...||...|.:.:|.|:..|...||::.|:::......:..:.:      ....|:|..|...
Mouse    75 IIVGMLGYCGTVKRNLLLLAWYFGTLLVIFCVELACGVWTYEQEVM------VPVQWSDMVTLKA 133

  Fly   123 RI---------------SLLEQKYSCCGQLGAHDYILMG-----------RGIPLSCYKDQERRE 161
            |:               :..::::.|||.:...|::.|.           |..| .|.|...:.:
Mouse   134 RMTNYGLPRYRWLTHAWNYFQREFKCCGVVYFTDWLEMTEMDWPPDSCCVREFP-GCSKQAHQED 197

  Fly   162 YS-LFSGGC 169
            .| |:..||
Mouse   198 LSDLYQEGC 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42En	NP_523640.1	Tetraspanin	8..>135	CDD:459767	31/156 (20%)
		tetraspanin_LEL	96..180	CDD:239401	17/101 (17%)
Tspan12	NP_766595.1	Tetraspanin	10..246	CDD:459767	43/204 (21%)
		TM4SF12_like_LEL	116..218	CDD:239410	17/98 (17%)