Protein Alignment Tsp42En and Tspan18

DIOPT Version :10

• Sequence 1: NP_523640.1
• Gene: Tsp42En / 35624
• FlyBaseID: FBgn0033135
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_899003.1
• Gene: Tspan18 / 241556
• MGIID: 1917186
• Length: 248
• Species: Mus musculus
• Alignment Length: 247
• Identity: 55/247 - (22%)
• Similarity: 89/247 - (36%)
• Gaps: 66/247 - (26%)

  Fly     2 DCRTSFLKAVLIVLNVLLSLIGVTLIALSVYELNSSTPGTFEHIAIVVQIFVGTFVVLT------ 60
            || .|.:|.::.|.|..:.|.|..|:.:.::.|...| |..|.:|....:..|.::||.
Mouse     4 DC-LSCMKYLMFVFNFFVFLGGACLLGVGIWVLVDPT-GFREIVATNPLLTTGAYIVLAMGGLLF 66

  Fly    61 --SFLGCFATARVSLGLVWSYVICLLILLCLQ-----IYIIAAAHST----------DYVERSKK 108
              .||||....|.:..|:..:.:.:||:..::     :..|...|.|          .|...:..
Mouse    67 LLGFLGCCGAVRENRCLLLFFFLFILIIFLVELSAAILAFIFREHLTREFFTKELTKHYQGDNDT 131

  Fly   109 D-FLATWADQRTNVERISLLEQKYSCCGQLGAHDYILMG---------RGIPLSCYKDQ------ 157
            | |.|||     |...|:     :.|||..|..|:.|..         ..:|.:|.:.:
Mouse   132 DVFSATW-----NSVMIT-----FGCCGVNGPEDFKLASVFRLLTLDTEEVPKACCRREPQTRDG 186

  Fly   158 ---ERREYSLFSG------GCLQAV------QAHATDNVAIGLIIKWLLLLV 194
               .|.|..|...      ||...:      ..:.....|||::...|.|:|
Mouse   187 VVLSREECQLGRNPFINKQGCYTVILNTFETYVYLAGAFAIGVLAIELFLMV 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42En	NP_523640.1	Tetraspanin	8..>135	CDD:459767	34/150 (23%)
		tetraspanin_LEL	96..180	CDD:239401	23/124 (19%)
Tspan18	NP_899003.1	Tetraspanin	10..245	CDD:459767	52/240 (22%)
		uroplakin_I_like_LEL	105..218	CDD:239409	24/122 (20%)