Protein Alignment lbm and CD81

DIOPT Version :10

• Sequence 1: NP_523639.1
• Gene: lbm / 35623
• FlyBaseID: FBgn0016032
• Length: 208
• Species: Drosophila melanogaster
• Sequence 2: XP_054226604.1
• Gene: CD81 / 975
• HGNCID: 1701
• Length: 335
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 53/214 - (24%)
• Similarity: 91/214 - (42%)
• Gaps: 38/214 - (17%)

  Fly    20 GFLAAGAIGWIAYNADTET------------EEFVIAAY--IACSLILVF-ALLGIFAAIRESVV 69
            |.:..|...|:.::..|..            ..|.:..|  ||...:::| ..||.:.||:||..
Human   124 GGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQC 188

  Fly    70 LTATSAVFLLILAILQIVSTCL-FLHEFDV-KSGRDMVEVAWQ-------ANNMDSLQQK-HE-- 122
            |..|....|:||...::.:... |:::..: |..:...:.|.|       |||..::.:. ||
Human   189 LLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHETL 253

  Fly   123 -CCGQSSAQDYIHLSLLIPPSCYADLQQTPDHLYLDGCIEKVQSFYESDKLRFI----IVSWVLV 182
             ||| ||....:..|:|....|.:. .....:|:.:.|.:|:...: |.||..|    ||..|::
Human   254 DCCG-SSTLTALTTSVLKNNLCPSG-SNIISNLFKEDCHQKIDDLF-SGKLYLIGIAAIVVAVIM 315

  Fly   183 AFELICFALAVFLAISFKN 201
            .||:|   |::.|....:|
Human   316 IFEMI---LSMVLCCGIRN 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbm	NP_523639.1	Tetraspanin	<47..196	CDD:459767	45/166 (27%)
		tetraspanin_LEL	<109..169	CDD:239401	17/70 (24%)
CD81	XP_054226604.1	Tetraspanin	122..327	CDD:459767	52/208 (25%)